향상된 2단계 미세입자 기반 국소 치료제 전달 시스템
점막 조직의 부위 또는 환자의 피부에 치료제를 전달하기 위한 시스템이 개시된다. 시스템은 1가 양이온의 염화물 염의 수용액 중 키토산을 포함하는 조성물에 의해 형성된 다공성 점착성, 동결 건조 매트릭스를 포함한다. 시스템은, 500 nm 내지 2000 nm의 평균 직경을 갖고 치료제를 포함하는 복수의 키토산 미세입자를 추가로 포함한다. A system is disclosed for delivery of a therapeutic agent to a site in mucosal tissue or to the skin of a patie...
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| creator | GOLDBERG MANIJEH N GOLDBERG ERIC R MANZI AARON M |
| description | 점막 조직의 부위 또는 환자의 피부에 치료제를 전달하기 위한 시스템이 개시된다. 시스템은 1가 양이온의 염화물 염의 수용액 중 키토산을 포함하는 조성물에 의해 형성된 다공성 점착성, 동결 건조 매트릭스를 포함한다. 시스템은, 500 nm 내지 2000 nm의 평균 직경을 갖고 치료제를 포함하는 복수의 키토산 미세입자를 추가로 포함한다.
A system is disclosed for delivery of a therapeutic agent to a site in mucosal tissue or to the skin of a patient. The system includes a porous mucoadhesive, freeze-dried matrix formed by a composition including chitosan in an aqueous salt solution of a chloride salt of a monovalent cation. The system further includes a plurality of chitosan microparticles having an average diameter between 500 nm and 2000 nm and comprising a therapeutic agent. |
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A system is disclosed for delivery of a therapeutic agent to a site in mucosal tissue or to the skin of a patient. The system includes a porous mucoadhesive, freeze-dried matrix formed by a composition including chitosan in an aqueous salt solution of a chloride salt of a monovalent cation. The system further includes a plurality of chitosan microparticles having an average diameter between 500 nm and 2000 nm and comprising a therapeutic agent.</description><language>kor</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240329&DB=EPODOC&CC=KR&NR=20240041285A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76517</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240329&DB=EPODOC&CC=KR&NR=20240041285A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GOLDBERG MANIJEH N</creatorcontrib><creatorcontrib>GOLDBERG ERIC R</creatorcontrib><creatorcontrib>MANZI AARON M</creatorcontrib><title>향상된 2단계 미세입자 기반 국소 치료제 전달 시스템</title><description>점막 조직의 부위 또는 환자의 피부에 치료제를 전달하기 위한 시스템이 개시된다. 시스템은 1가 양이온의 염화물 염의 수용액 중 키토산을 포함하는 조성물에 의해 형성된 다공성 점착성, 동결 건조 매트릭스를 포함한다. 시스템은, 500 nm 내지 2000 nm의 평균 직경을 갖고 치료제를 포함하는 복수의 키토산 미세입자를 추가로 포함한다.
A system is disclosed for delivery of a therapeutic agent to a site in mucosal tissue or to the skin of a patient. The system includes a porous mucoadhesive, freeze-dried matrix formed by a composition including chitosan in an aqueous salt solution of a chloride salt of a monovalent cation. The system further includes a plurality of chitosan microparticles having an average diameter between 500 nm and 2000 nm and comprising a therapeutic agent.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB_O23pm-bG1xPmKBi97l7xanOLwuv1O9607Hgzr_XNvAkKr3ZseL1hhsKrrWvftPUovNk54_XinjcL5ii8WdDyunuNwpvuOW-6lrxtncPDwJqWmFOcyguluRmU3VxDnD10Uwvy41OLCxKTU_NSS-K9g4wMjEwMDEwMjSxMHY2JUwUAx7JH4A</recordid><startdate>20240329</startdate><enddate>20240329</enddate><creator>GOLDBERG MANIJEH N</creator><creator>GOLDBERG ERIC R</creator><creator>MANZI AARON M</creator><scope>EVB</scope></search><sort><creationdate>20240329</creationdate><title>향상된 2단계 미세입자 기반 국소 치료제 전달 시스템</title><author>GOLDBERG MANIJEH N ; GOLDBERG ERIC R ; MANZI AARON M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20240041285A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GOLDBERG MANIJEH N</creatorcontrib><creatorcontrib>GOLDBERG ERIC R</creatorcontrib><creatorcontrib>MANZI AARON M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GOLDBERG MANIJEH N</au><au>GOLDBERG ERIC R</au><au>MANZI AARON M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>향상된 2단계 미세입자 기반 국소 치료제 전달 시스템</title><date>2024-03-29</date><risdate>2024</risdate><abstract>점막 조직의 부위 또는 환자의 피부에 치료제를 전달하기 위한 시스템이 개시된다. 시스템은 1가 양이온의 염화물 염의 수용액 중 키토산을 포함하는 조성물에 의해 형성된 다공성 점착성, 동결 건조 매트릭스를 포함한다. 시스템은, 500 nm 내지 2000 nm의 평균 직경을 갖고 치료제를 포함하는 복수의 키토산 미세입자를 추가로 포함한다.
A system is disclosed for delivery of a therapeutic agent to a site in mucosal tissue or to the skin of a patient. The system includes a porous mucoadhesive, freeze-dried matrix formed by a composition including chitosan in an aqueous salt solution of a chloride salt of a monovalent cation. The system further includes a plurality of chitosan microparticles having an average diameter between 500 nm and 2000 nm and comprising a therapeutic agent.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 향상된 2단계 미세입자 기반 국소 치료제 전달 시스템 |
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