암의 치료에 사용하기 위한 마스킹된 유형 I 인터페론 (IFNα 및 IFNβ)을 포함하는 융합 단백질 조성물 및 그의 방법
마스킹된 IFN을 포함하는 융합 단백질 조성물 및 마스킹된 IFN을 제조하는 방법이 본원에 개시된다. 결과적으로, 마스킹된 IFN은 Mab 또는 그의 결합 단편에 융합되고, 치료 양식으로서 환자에게 투여되고, 암, 면역학적 장애 및 다른 질환을 치료하는 방법을 제공할 수 있다. Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be...
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| creator | VASUTHASAWAT ALEX TRIHN KHAM STOVER DAVID MORRISON SHERIE |
| description | 마스킹된 IFN을 포함하는 융합 단백질 조성물 및 마스킹된 IFN을 제조하는 방법이 본원에 개시된다. 결과적으로, 마스킹된 IFN은 Mab 또는 그의 결합 단편에 융합되고, 치료 양식으로서 환자에게 투여되고, 암, 면역학적 장애 및 다른 질환을 치료하는 방법을 제공할 수 있다.
Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease. |
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Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 암의 치료에 사용하기 위한 마스킹된 유형 I 인터페론 (IFNα 및 IFNβ)을 포함하는 융합 단백질 조성물 및 그의 방법 |
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