DDR 억제제로서의 인돌린 유도체

본 발명은 디스코이딘 도메인 수용체(Discoidin Domain Receptors)를 억제하는 일반식(I)의 화합물(DDR 억제제), 상기 화합물을 제조하는 방법, 이들을 가지고 있는 약제학적 조성물 및 이들의 치료학적 사용에 관한 것이다. 본 발명의 화합물은 예를 들어 DDR 매커니즘과 연관된 많은 질병의 치료에 유용할 수 있다. JPEGpct00238.jpg4361 The present invention relates to compounds of general formula (I) inhibiting Discoidin Doma...

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Hauptverfasser: KNIGHT KEITH CHRISTOPHER, IOTTI NICOLO, MULLINS TOBY MATTHEW GROVER, CARZANIGA LAURA, WHITTAKER BEN PAUL, RANCATI FABIO, RIZZI ANDREA, KARAWAJCZYK ANNA
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creator KNIGHT KEITH CHRISTOPHER
IOTTI NICOLO
MULLINS TOBY MATTHEW GROVER
CARZANIGA LAURA
WHITTAKER BEN PAUL
RANCATI FABIO
RIZZI ANDREA
KARAWAJCZYK ANNA
description 본 발명은 디스코이딘 도메인 수용체(Discoidin Domain Receptors)를 억제하는 일반식(I)의 화합물(DDR 억제제), 상기 화합물을 제조하는 방법, 이들을 가지고 있는 약제학적 조성물 및 이들의 치료학적 사용에 관한 것이다. 본 발명의 화합물은 예를 들어 DDR 매커니즘과 연관된 많은 질병의 치료에 유용할 수 있다. JPEGpct00238.jpg4361 The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DDR 억제제로서의 인돌린 유도체
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