3 Method for preparing user-friendly 3D gut-on-a-chip using villi-shaped membrane

The present invention relates to a three-dimensional intestinal chip using a membrane in the shape of a villus and a three-dimensional culture method of intestinal epithelial cells using the same. When using the intestinal chip of the present invention, the manufacturing method is more convenient th...

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Bibliographische Detailangaben
Hauptverfasser:	PARK SUNGSU, KIM MINHYEOK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a three-dimensional intestinal chip using a membrane in the shape of a villus and a three-dimensional culture method of intestinal epithelial cells using the same. When using the intestinal chip of the present invention, the manufacturing method is more convenient than the conventional method using hydrogel, and the culture may be performed in a very short time, and an environment closer to in vivo intestinal tissue is created, so that it may be usefully used in research related to various intestinal cells. 본 발명은 융모 형상의 멤브레인을 이용한 3차원 장 칩 및 이를 이용한 장 상피세포의 3차원 배양 방법에 관한 것이다. 본 발명의 장 칩을 이용하는 경우 종래 하이드로겔을 이용하는 방식에 비하여 더 제조 방법이 편리하면서도, 매우 단시간에 배양이 가능하고 in vivo 장 조직에 보다 가까운 환경을 조성함으로써 다양한 장 세포와 관련된 연구에 유용하게 사용될 수 있다.