RAGE AGE Pharmaceutical Composition for Preventing or Treating Stroke with Diabetic Comprising RAGE Antagonist or AGE scavenger

The present invention relates to a pharmaceutical composition for preventing or treating diabetic stroke comprising at least one of a receptor for advanced glycation endproducts (RAGE) antagonist or an advanced glycation endproducts (AGE) scavenger, wherein the composition, when administered to a su...

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Bibliographische Detailangaben
Hauptverfasser:	YOON BOK SEON, LEE JIN SOO
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical composition for preventing or treating diabetic stroke comprising at least one of a receptor for advanced glycation endproducts (RAGE) antagonist or an advanced glycation endproducts (AGE) scavenger, wherein the composition, when administered to a subject, prevents or treats a stroke with high blood sugar. More specifically, administering the composition to a subject has an effect of inhibiting brain damage caused by stroke with high blood sugar. 본 발명은 RAGE (receptor for advanced glycation endproducts) 길항제 또는 AGE (advanced glycation endproducts) 소거제 중 하나 이상을 포함하는 당뇨성 뇌졸중 예방 또는 치료용 약학적 조성물에 관한 것으로, 상기 조성물을 개체에 투여하면 고혈당을 동반한 뇌졸중을 예방 또는 치료할 수 있다. 더 구체적으로, 상기 조성물을 개체에 투여하면 고혈당을 동반한 뇌졸중으로 인하여 뇌가 손상되는 것을 억제하는 효과가 있다.