암 치료를 위한 템플릿 지시된 면역조절

비종양 환경에 비해 종양 미세환경에서 많이 발현되는 miRNA에 상보적인 단일 가닥 5' 언캡핑 트리포스페이트 또는 바이포스페이트 변형된 RNA 올리고뉴클레오티드를 포함하는 암 치료용 조성물 및 치료 방법이 본원에 기재되어 있다. Described herein are compositions and methods for treating cancer comprising single-stranded 5′ uncapped triphosphate or biphosphate modified RNA oligonucleotides com...

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Hauptverfasser: LIU QIYONG PETER, GHOSH SUBRATA KUMAR, DUDLEY ROBERT MICHAEL
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creator LIU QIYONG PETER
GHOSH SUBRATA KUMAR
DUDLEY ROBERT MICHAEL
description 비종양 환경에 비해 종양 미세환경에서 많이 발현되는 miRNA에 상보적인 단일 가닥 5' 언캡핑 트리포스페이트 또는 바이포스페이트 변형된 RNA 올리고뉴클레오티드를 포함하는 암 치료용 조성물 및 치료 방법이 본원에 기재되어 있다. Described herein are compositions and methods for treating cancer comprising single-stranded 5′ uncapped triphosphate or biphosphate modified RNA oligonucleotides complementary to a miRNA which is highly expressed in a tumor microenvironment in comparison to a non-tumor environment.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title 암 치료를 위한 템플릿 지시된 면역조절
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