2- TEAD Novel 2-phenylaminopyridine-based TEAD inhibitor and pharmaceutical composition comprising the same

The present invention relates to a novel 2-(phenylamino)pyridine derivative and a pharmaceutical composition for the prevention or treatment of cancer containing the same as an active ingredient. The compound represented by chemical formula 1 described herein has excellent inhibitory activity agains...

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Bibliographische Detailangaben
Hauptverfasser:	OH YOOJUNG, CHOI YONG SUNG, KANG SEOK GU, KIM YOON JUNG, CHOI RAN JOO, JEON RAOK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a novel 2-(phenylamino)pyridine derivative and a pharmaceutical composition for the prevention or treatment of cancer containing the same as an active ingredient. The compound represented by chemical formula 1 described herein has excellent inhibitory activity against TEAD, and it is expected to be useful in the prevention or treatment of cancer. 본 발명은 신규한 2-(페닐아미노)피리딘 유도체, 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 명세서에 기재된 화학식 1로 표시되는 화합물은 TEAD에 대한 우수한 억제 활성을 나타내면서, 암의 예방 또는 치료에 유용할 것으로 기대된다.