ROR1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법

항-ROR1 항체 모이어티, 특히 키메라 항원 수용체(CAR)를 포함하는 재조합 수용체에 존재하는 항-ROR1 항체 모이어티를 특이적으로 인식하는 항-이디오타입 항체가 제공된다. 본 개시내용은 또한 이러한 재조합 수용체를 발현하는 세포, 예컨대 항-ROR1 CAR T 세포를 특이적으로 확인 및/또는 선택하기 위한 항-이디오타입 항체의 용도에 관한 것이다. 본 개시내용은 또한 이러한 세포를 특이적으로 차단하거나 활성화하기 위한 항-이디오타입 항체의 용도에 관한 것이다. Provided are anti-idiotype antibodie...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	OH YEONJOO, COSTA ANDREIA, HAUSKINS COLLIN, SIERRA CATHERINE
Format:	Patent
Sprache:	kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	OH YEONJOO COSTA ANDREIA HAUSKINS COLLIN SIERRA CATHERINE
description	항-ROR1 항체 모이어티, 특히 키메라 항원 수용체(CAR)를 포함하는 재조합 수용체에 존재하는 항-ROR1 항체 모이어티를 특이적으로 인식하는 항-이디오타입 항체가 제공된다. 본 개시내용은 또한 이러한 재조합 수용체를 발현하는 세포, 예컨대 항-ROR1 CAR T 세포를 특이적으로 확인 및/또는 선택하기 위한 항-이디오타입 항체의 용도에 관한 것이다. 본 개시내용은 또한 이러한 세포를 특이적으로 차단하거나 활성화하기 위한 항-이디오타입 항체의 용도에 관한 것이다. Provided are anti-idiotype antibodies that specifically recognize anti-ROR1 antibody moieties, in particular, anti-ROR1 antibody moieties present in recombinant receptors, including chimeric antigen receptors (CARs). The disclosure further relates to uses of anti-idiotype antibodies for specifically identifying and/or selecting cells expressing such recombinant receptors, such as anti-ROR1 CAR T cells. The disclosure further relates to uses of anti-idiotype antibodies for specifically blocking or activating such cells.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20230095918A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20230095918A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20230095918A3</originalsourceid><addsrcrecordid>eNrjZEgI8g8y1H07cc6bBY0KrzZteDt1pcLr_pbXK6e8mbvjzfQJCq97Gt5OnaPwduraN3O3vJ4y5c2MJW-bG97MawULbdqi8HpDv8KrLQ2vF6xQeLNww5uWja_X7AELvt6w8vWmqTwMrGmJOcWpvFCam0HZzTXE2UM3tSA_PrW4IDE5NS-1JN47yMjAyNjAwNLU0tDC0Zg4VQDy9lbi</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ROR1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법</title><source>esp@cenet</source><creator>OH YEONJOO ; COSTA ANDREIA ; HAUSKINS COLLIN ; SIERRA CATHERINE</creator><creatorcontrib>OH YEONJOO ; COSTA ANDREIA ; HAUSKINS COLLIN ; SIERRA CATHERINE</creatorcontrib><description>항-ROR1 항체 모이어티, 특히 키메라 항원 수용체(CAR)를 포함하는 재조합 수용체에 존재하는 항-ROR1 항체 모이어티를 특이적으로 인식하는 항-이디오타입 항체가 제공된다. 본 개시내용은 또한 이러한 재조합 수용체를 발현하는 세포, 예컨대 항-ROR1 CAR T 세포를 특이적으로 확인 및/또는 선택하기 위한 항-이디오타입 항체의 용도에 관한 것이다. 본 개시내용은 또한 이러한 세포를 특이적으로 차단하거나 활성화하기 위한 항-이디오타입 항체의 용도에 관한 것이다. Provided are anti-idiotype antibodies that specifically recognize anti-ROR1 antibody moieties, in particular, anti-ROR1 antibody moieties present in recombinant receptors, including chimeric antigen receptors (CARs). The disclosure further relates to uses of anti-idiotype antibodies for specifically identifying and/or selecting cells expressing such recombinant receptors, such as anti-ROR1 CAR T cells. The disclosure further relates to uses of anti-idiotype antibodies for specifically blocking or activating such cells.</description><language>kor</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230629&DB=EPODOC&CC=KR&NR=20230095918A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230629&DB=EPODOC&CC=KR&NR=20230095918A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OH YEONJOO</creatorcontrib><creatorcontrib>COSTA ANDREIA</creatorcontrib><creatorcontrib>HAUSKINS COLLIN</creatorcontrib><creatorcontrib>SIERRA CATHERINE</creatorcontrib><title>ROR1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법</title><description>항-ROR1 항체 모이어티, 특히 키메라 항원 수용체(CAR)를 포함하는 재조합 수용체에 존재하는 항-ROR1 항체 모이어티를 특이적으로 인식하는 항-이디오타입 항체가 제공된다. 본 개시내용은 또한 이러한 재조합 수용체를 발현하는 세포, 예컨대 항-ROR1 CAR T 세포를 특이적으로 확인 및/또는 선택하기 위한 항-이디오타입 항체의 용도에 관한 것이다. 본 개시내용은 또한 이러한 세포를 특이적으로 차단하거나 활성화하기 위한 항-이디오타입 항체의 용도에 관한 것이다. Provided are anti-idiotype antibodies that specifically recognize anti-ROR1 antibody moieties, in particular, anti-ROR1 antibody moieties present in recombinant receptors, including chimeric antigen receptors (CARs). The disclosure further relates to uses of anti-idiotype antibodies for specifically identifying and/or selecting cells expressing such recombinant receptors, such as anti-ROR1 CAR T cells. The disclosure further relates to uses of anti-idiotype antibodies for specifically blocking or activating such cells.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZEgI8g8y1H07cc6bBY0KrzZteDt1pcLr_pbXK6e8mbvjzfQJCq97Gt5OnaPwduraN3O3vJ4y5c2MJW-bG97MawULbdqi8HpDv8KrLQ2vF6xQeLNww5uWja_X7AELvt6w8vWmqTwMrGmJOcWpvFCam0HZzTXE2UM3tSA_PrW4IDE5NS-1JN47yMjAyNjAwNLU0tDC0Zg4VQDy9lbi</recordid><startdate>20230629</startdate><enddate>20230629</enddate><creator>OH YEONJOO</creator><creator>COSTA ANDREIA</creator><creator>HAUSKINS COLLIN</creator><creator>SIERRA CATHERINE</creator><scope>EVB</scope></search><sort><creationdate>20230629</creationdate><title>ROR1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법</title><author>OH YEONJOO ; COSTA ANDREIA ; HAUSKINS COLLIN ; SIERRA CATHERINE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20230095918A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>OH YEONJOO</creatorcontrib><creatorcontrib>COSTA ANDREIA</creatorcontrib><creatorcontrib>HAUSKINS COLLIN</creatorcontrib><creatorcontrib>SIERRA CATHERINE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OH YEONJOO</au><au>COSTA ANDREIA</au><au>HAUSKINS COLLIN</au><au>SIERRA CATHERINE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ROR1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법</title><date>2023-06-29</date><risdate>2023</risdate><abstract>항-ROR1 항체 모이어티, 특히 키메라 항원 수용체(CAR)를 포함하는 재조합 수용체에 존재하는 항-ROR1 항체 모이어티를 특이적으로 인식하는 항-이디오타입 항체가 제공된다. 본 개시내용은 또한 이러한 재조합 수용체를 발현하는 세포, 예컨대 항-ROR1 CAR T 세포를 특이적으로 확인 및/또는 선택하기 위한 항-이디오타입 항체의 용도에 관한 것이다. 본 개시내용은 또한 이러한 세포를 특이적으로 차단하거나 활성화하기 위한 항-이디오타입 항체의 용도에 관한 것이다. Provided are anti-idiotype antibodies that specifically recognize anti-ROR1 antibody moieties, in particular, anti-ROR1 antibody moieties present in recombinant receptors, including chimeric antigen receptors (CARs). The disclosure further relates to uses of anti-idiotype antibodies for specifically identifying and/or selecting cells expressing such recombinant receptors, such as anti-ROR1 CAR T cells. The disclosure further relates to uses of anti-idiotype antibodies for specifically blocking or activating such cells.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	kor
recordid	cdi_epo_espacenet_KR20230095918A
source	esp@cenet
subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
title	ROR1-표적 결합 도메인에 대한 항이디오타입 항체 및 관련 조성물 및 방법
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T18%3A13%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=OH%20YEONJOO&rft.date=2023-06-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EKR20230095918A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true