Tangshenoside I Pharmaceutical composition for preventing or treating muscle disease containing Tangshenoside I as an active ingredient
The present invention relates to a pharmaceutical composition for preventing or treating muscle diseases containing Tangsenoside I as an active ingredient. Tangsenoside I of the present invention alleviates the decrease in muscle weight and muscle fiber cross-sectional area due to muscle atrophy, al...
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| creator | HAN JONG KWON JEON YONGJAE PARK KEUN TAE KIM SEONG JIN OH MI HYANG KIM YI JOON CHOUNG SE YOUNG |
| description | The present invention relates to a pharmaceutical composition for preventing or treating muscle diseases containing Tangsenoside I as an active ingredient. Tangsenoside I of the present invention alleviates the decrease in muscle weight and muscle fiber cross-sectional area due to muscle atrophy, alleviates the increased expression of factors involved in the breakdown of muscle proteins, increases the expression of factors involved in the synthesis of muscle proteins, and increases the expression of factors involved in mitochondrial biogenesis, which plays an important role in energy distribution within muscle cells, thereby being able to be usefully used for preventing, alleviating or treating muscle diseases.
본 발명은 탕세노사이드 I을 유효성분으로 포함하는 근육 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명의 탕세노사이드 I은 근위축에 따른 근육 무게 및 근섬유 단면적의 감소를 완화시키고, 근육 단백질의 분해에 관여하는 인자의 발현 증가를 완화시키고, 근육 단백질의 합성에 관여하는 인자의 발현을 증가시키며, 근육 세포 내 에너지 분포에 중요한 역할을 하는 미토콘드리아 생합성에 관여하는 인자의 발현을 증가시킴으로써, 근육 질환을 예방, 개선 또는 치료하는데 유용하게 이용될 수 있다. |
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본 발명은 탕세노사이드 I을 유효성분으로 포함하는 근육 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명의 탕세노사이드 I은 근위축에 따른 근육 무게 및 근섬유 단면적의 감소를 완화시키고, 근육 단백질의 분해에 관여하는 인자의 발현 증가를 완화시키고, 근육 단백질의 합성에 관여하는 인자의 발현을 증가시키며, 근육 세포 내 에너지 분포에 중요한 역할을 하는 미토콘드리아 생합성에 관여하는 인자의 발현을 증가시킴으로써, 근육 질환을 예방, 개선 또는 치료하는데 유용하게 이용될 수 있다.</description><language>eng ; kor</language><subject>FODDER ; FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230517&DB=EPODOC&CC=KR&NR=20230067724A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230517&DB=EPODOC&CC=KR&NR=20230067724A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAN JONG KWON</creatorcontrib><creatorcontrib>JEON YONGJAE</creatorcontrib><creatorcontrib>PARK KEUN TAE</creatorcontrib><creatorcontrib>KIM SEONG JIN</creatorcontrib><creatorcontrib>OH MI HYANG</creatorcontrib><creatorcontrib>KIM YI JOON</creatorcontrib><creatorcontrib>CHOUNG SE YOUNG</creatorcontrib><title>Tangshenoside I Pharmaceutical composition for preventing or treating muscle disease containing Tangshenoside I as an active ingredient</title><description>The present invention relates to a pharmaceutical composition for preventing or treating muscle diseases containing Tangsenoside I as an active ingredient. Tangsenoside I of the present invention alleviates the decrease in muscle weight and muscle fiber cross-sectional area due to muscle atrophy, alleviates the increased expression of factors involved in the breakdown of muscle proteins, increases the expression of factors involved in the synthesis of muscle proteins, and increases the expression of factors involved in mitochondrial biogenesis, which plays an important role in energy distribution within muscle cells, thereby being able to be usefully used for preventing, alleviating or treating muscle diseases.
본 발명은 탕세노사이드 I을 유효성분으로 포함하는 근육 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명의 탕세노사이드 I은 근위축에 따른 근육 무게 및 근섬유 단면적의 감소를 완화시키고, 근육 단백질의 분해에 관여하는 인자의 발현 증가를 완화시키고, 근육 단백질의 합성에 관여하는 인자의 발현을 증가시키며, 근육 세포 내 에너지 분포에 중요한 역할을 하는 미토콘드리아 생합성에 관여하는 인자의 발현을 증가시킴으로써, 근육 질환을 예방, 개선 또는 치료하는데 유용하게 이용될 수 있다.</description><subject>FODDER</subject><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTrsKwkAQTGMh6j8sWAshEVMHURQbkfRhuWyShWTvuL3kF_xtT7GyspoZ5sEsk2eF0mlPYpUbgivce_QjGpoCGxzA2NFFK7AVaK0H52kmCSwdRBU84YePk5qBoGElVIotCcjydn73UQEF0ASeCWLAU8NxcJ0sWhyUNl9cJdvzqTpeduRsTeriI6FQ3x5ZmuVpeiiKbF_m_6VeMdNNbg</recordid><startdate>20230517</startdate><enddate>20230517</enddate><creator>HAN JONG KWON</creator><creator>JEON YONGJAE</creator><creator>PARK KEUN TAE</creator><creator>KIM SEONG JIN</creator><creator>OH MI HYANG</creator><creator>KIM YI JOON</creator><creator>CHOUNG SE YOUNG</creator><scope>EVB</scope></search><sort><creationdate>20230517</creationdate><title>Tangshenoside I Pharmaceutical composition for preventing or treating muscle disease containing Tangshenoside I as an active ingredient</title><author>HAN JONG KWON ; JEON YONGJAE ; PARK KEUN TAE ; KIM SEONG JIN ; OH MI HYANG ; KIM YI JOON ; CHOUNG SE YOUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20230067724A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2023</creationdate><topic>FODDER</topic><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>HAN JONG KWON</creatorcontrib><creatorcontrib>JEON YONGJAE</creatorcontrib><creatorcontrib>PARK KEUN TAE</creatorcontrib><creatorcontrib>KIM SEONG JIN</creatorcontrib><creatorcontrib>OH MI HYANG</creatorcontrib><creatorcontrib>KIM YI JOON</creatorcontrib><creatorcontrib>CHOUNG SE YOUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HAN JONG KWON</au><au>JEON YONGJAE</au><au>PARK KEUN TAE</au><au>KIM SEONG JIN</au><au>OH MI HYANG</au><au>KIM YI JOON</au><au>CHOUNG SE YOUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Tangshenoside I Pharmaceutical composition for preventing or treating muscle disease containing Tangshenoside I as an active ingredient</title><date>2023-05-17</date><risdate>2023</risdate><abstract>The present invention relates to a pharmaceutical composition for preventing or treating muscle diseases containing Tangsenoside I as an active ingredient. Tangsenoside I of the present invention alleviates the decrease in muscle weight and muscle fiber cross-sectional area due to muscle atrophy, alleviates the increased expression of factors involved in the breakdown of muscle proteins, increases the expression of factors involved in the synthesis of muscle proteins, and increases the expression of factors involved in mitochondrial biogenesis, which plays an important role in energy distribution within muscle cells, thereby being able to be usefully used for preventing, alleviating or treating muscle diseases.
본 발명은 탕세노사이드 I을 유효성분으로 포함하는 근육 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명의 탕세노사이드 I은 근위축에 따른 근육 무게 및 근섬유 단면적의 감소를 완화시키고, 근육 단백질의 분해에 관여하는 인자의 발현 증가를 완화시키고, 근육 단백질의 합성에 관여하는 인자의 발현을 증가시키며, 근육 세포 내 에너지 분포에 중요한 역할을 하는 미토콘드리아 생합성에 관여하는 인자의 발현을 증가시킴으로써, 근육 질환을 예방, 개선 또는 치료하는데 유용하게 이용될 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | FODDER FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Tangshenoside I Pharmaceutical composition for preventing or treating muscle disease containing Tangshenoside I as an active ingredient |
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