항-B7-H3 항체를 포함하는 항체-약물 접합체
본 개시내용은 항체-약물 접합체(ADC)에 관한 것이되, 하나 이상의 활성제는 링커를 통해 항-B7-H3 항체에 접합된다. 링커는 활성제를 항체에 공유적으로 연결하는 단위를 포함할 수 있다. 본 개시내용은 추가로 B7-H3에 특이적으로 결합하는 단일클론 항체 및 이의 항원 결합 단편, 변이체, 다량체 버전 또는 이중특이성뿐만 아니라 다양한 치료적, 진단적 및 예방적 적응증에서 이러한 항-B7-H3 항체 및 이의 항원-결합 단편을 제조하고 사용하는 방법에 관한 것이다. The present disclosure relates to an...
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| creator | PARK JAE EUN LEE EUNJIN SEO DONGHOON LEE HYANG SOOK LEE MINJU LEE SANGKWANG JUNG DOOHWAN PARK YOUNG WOO YUN SANGHYEON PARK SUHO KIM SUNYOUNG PARK OKKU WOO SUNG HO KIM SENA REW YOSUP LEE JAEHO KO YUNJUNG CHO JONGUN SEOL MINAH SONG YOUNGJA HA JIHYEON SONG JINA LEE HYUN MI LEE HYUN JU SHIM EUN YOUNG PARK TAEKYO SEO BEOMSEOK |
| description | 본 개시내용은 항체-약물 접합체(ADC)에 관한 것이되, 하나 이상의 활성제는 링커를 통해 항-B7-H3 항체에 접합된다. 링커는 활성제를 항체에 공유적으로 연결하는 단위를 포함할 수 있다. 본 개시내용은 추가로 B7-H3에 특이적으로 결합하는 단일클론 항체 및 이의 항원 결합 단편, 변이체, 다량체 버전 또는 이중특이성뿐만 아니라 다양한 치료적, 진단적 및 예방적 적응증에서 이러한 항-B7-H3 항체 및 이의 항원-결합 단편을 제조하고 사용하는 방법에 관한 것이다.
The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20230028793A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20230028793A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20230028793A3</originalsourceid><addsrcrecordid>eNrjZLB4O3WtrpO5roexApD1ZtOW10v3KLztX_N26oq3U2e87poCFdZ9M3Xv6zV7FN4smPh26kqgAA8Da1piTnEqL5TmZlB2cw1x9tBNLciPTy0uSExOzUstifcOMjIwMjYwMLIwtzR2NCZOFQASlz0b</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>항-B7-H3 항체를 포함하는 항체-약물 접합체</title><source>esp@cenet</source><creator>PARK JAE EUN ; LEE EUNJIN ; SEO DONGHOON ; LEE HYANG SOOK ; LEE MINJU ; LEE SANGKWANG ; JUNG DOOHWAN ; PARK YOUNG WOO ; YUN SANGHYEON ; PARK SUHO ; KIM SUNYOUNG ; PARK OKKU ; WOO SUNG HO ; KIM SENA ; REW YOSUP ; LEE JAEHO ; KO YUNJUNG ; CHO JONGUN ; SEOL MINAH ; SONG YOUNGJA ; HA JIHYEON ; SONG JINA ; LEE HYUN MI ; LEE HYUN JU ; SHIM EUN YOUNG ; PARK TAEKYO ; SEO BEOMSEOK</creator><creatorcontrib>PARK JAE EUN ; LEE EUNJIN ; SEO DONGHOON ; LEE HYANG SOOK ; LEE MINJU ; LEE SANGKWANG ; JUNG DOOHWAN ; PARK YOUNG WOO ; YUN SANGHYEON ; PARK SUHO ; KIM SUNYOUNG ; PARK OKKU ; WOO SUNG HO ; KIM SENA ; REW YOSUP ; LEE JAEHO ; KO YUNJUNG ; CHO JONGUN ; SEOL MINAH ; SONG YOUNGJA ; HA JIHYEON ; SONG JINA ; LEE HYUN MI ; LEE HYUN JU ; SHIM EUN YOUNG ; PARK TAEKYO ; SEO BEOMSEOK</creatorcontrib><description>본 개시내용은 항체-약물 접합체(ADC)에 관한 것이되, 하나 이상의 활성제는 링커를 통해 항-B7-H3 항체에 접합된다. 링커는 활성제를 항체에 공유적으로 연결하는 단위를 포함할 수 있다. 본 개시내용은 추가로 B7-H3에 특이적으로 결합하는 단일클론 항체 및 이의 항원 결합 단편, 변이체, 다량체 버전 또는 이중특이성뿐만 아니라 다양한 치료적, 진단적 및 예방적 적응증에서 이러한 항-B7-H3 항체 및 이의 항원-결합 단편을 제조하고 사용하는 방법에 관한 것이다.
The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.</description><language>kor</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230302&DB=EPODOC&CC=KR&NR=20230028793A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230302&DB=EPODOC&CC=KR&NR=20230028793A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PARK JAE EUN</creatorcontrib><creatorcontrib>LEE EUNJIN</creatorcontrib><creatorcontrib>SEO DONGHOON</creatorcontrib><creatorcontrib>LEE HYANG SOOK</creatorcontrib><creatorcontrib>LEE MINJU</creatorcontrib><creatorcontrib>LEE SANGKWANG</creatorcontrib><creatorcontrib>JUNG DOOHWAN</creatorcontrib><creatorcontrib>PARK YOUNG WOO</creatorcontrib><creatorcontrib>YUN SANGHYEON</creatorcontrib><creatorcontrib>PARK SUHO</creatorcontrib><creatorcontrib>KIM SUNYOUNG</creatorcontrib><creatorcontrib>PARK OKKU</creatorcontrib><creatorcontrib>WOO SUNG HO</creatorcontrib><creatorcontrib>KIM SENA</creatorcontrib><creatorcontrib>REW YOSUP</creatorcontrib><creatorcontrib>LEE JAEHO</creatorcontrib><creatorcontrib>KO YUNJUNG</creatorcontrib><creatorcontrib>CHO JONGUN</creatorcontrib><creatorcontrib>SEOL MINAH</creatorcontrib><creatorcontrib>SONG YOUNGJA</creatorcontrib><creatorcontrib>HA JIHYEON</creatorcontrib><creatorcontrib>SONG JINA</creatorcontrib><creatorcontrib>LEE HYUN MI</creatorcontrib><creatorcontrib>LEE HYUN JU</creatorcontrib><creatorcontrib>SHIM EUN YOUNG</creatorcontrib><creatorcontrib>PARK TAEKYO</creatorcontrib><creatorcontrib>SEO BEOMSEOK</creatorcontrib><title>항-B7-H3 항체를 포함하는 항체-약물 접합체</title><description>본 개시내용은 항체-약물 접합체(ADC)에 관한 것이되, 하나 이상의 활성제는 링커를 통해 항-B7-H3 항체에 접합된다. 링커는 활성제를 항체에 공유적으로 연결하는 단위를 포함할 수 있다. 본 개시내용은 추가로 B7-H3에 특이적으로 결합하는 단일클론 항체 및 이의 항원 결합 단편, 변이체, 다량체 버전 또는 이중특이성뿐만 아니라 다양한 치료적, 진단적 및 예방적 적응증에서 이러한 항-B7-H3 항체 및 이의 항원-결합 단편을 제조하고 사용하는 방법에 관한 것이다.
The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB4O3WtrpO5roexApD1ZtOW10v3KLztX_N26oq3U2e87poCFdZ9M3Xv6zV7FN4smPh26kqgAA8Da1piTnEqL5TmZlB2cw1x9tBNLciPTy0uSExOzUstifcOMjIwMjYwMLIwtzR2NCZOFQASlz0b</recordid><startdate>20230302</startdate><enddate>20230302</enddate><creator>PARK JAE EUN</creator><creator>LEE EUNJIN</creator><creator>SEO DONGHOON</creator><creator>LEE HYANG SOOK</creator><creator>LEE MINJU</creator><creator>LEE SANGKWANG</creator><creator>JUNG DOOHWAN</creator><creator>PARK YOUNG WOO</creator><creator>YUN SANGHYEON</creator><creator>PARK SUHO</creator><creator>KIM SUNYOUNG</creator><creator>PARK OKKU</creator><creator>WOO SUNG HO</creator><creator>KIM SENA</creator><creator>REW YOSUP</creator><creator>LEE JAEHO</creator><creator>KO YUNJUNG</creator><creator>CHO JONGUN</creator><creator>SEOL MINAH</creator><creator>SONG YOUNGJA</creator><creator>HA JIHYEON</creator><creator>SONG JINA</creator><creator>LEE HYUN MI</creator><creator>LEE HYUN JU</creator><creator>SHIM EUN YOUNG</creator><creator>PARK TAEKYO</creator><creator>SEO BEOMSEOK</creator><scope>EVB</scope></search><sort><creationdate>20230302</creationdate><title>항-B7-H3 항체를 포함하는 항체-약물 접합체</title><author>PARK JAE EUN ; 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The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.</abstract><oa>free_for_read</oa></addata></record> |
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| title | 항-B7-H3 항체를 포함하는 항체-약물 접합체 |
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