알파-1 프로테이나제 억제제를 얻기 위한 방법

고농축된 알파-1 프로테이나제 억제제 (A1PI)를 얻기 위한 방법으로서, 물에 대한 접선 흐름 여과 (TFF)에 의해 A1PI의 초기 용액을 농축시킴으로써 A1PI의 용액을 제조하는 단계를 포함하고, 여기서 농축된 용액에서의 A1PI의 최종 농도는 적어도 110 mg/ml이다. A method for obtaining Alpha-1 Proteinase Inhibitor for obtaining highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) includes preparing a...

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Hauptverfasser: YUZIUK JEFFREY A, REBBEOR JAMES, MCBRIDE DENNIS, GRADY GEORGE
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creator YUZIUK JEFFREY A
REBBEOR JAMES
MCBRIDE DENNIS
GRADY GEORGE
description 고농축된 알파-1 프로테이나제 억제제 (A1PI)를 얻기 위한 방법으로서, 물에 대한 접선 흐름 여과 (TFF)에 의해 A1PI의 초기 용액을 농축시킴으로써 A1PI의 용액을 제조하는 단계를 포함하고, 여기서 농축된 용액에서의 A1PI의 최종 농도는 적어도 110 mg/ml이다. A method for obtaining Alpha-1 Proteinase Inhibitor for obtaining highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) includes preparing a solution of A1PI by concentrating an initial solution of A1PI by tangential flow filtration (TFF) against water. The final concentration of A1PI in the concentrated solution is at least 110 mg/ml. The TFF can be carried out against water for injection (WFD).
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title 알파-1 프로테이나제 억제제를 얻기 위한 방법
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