헤테로시클릭 PAD4 억제제
본 개시내용은 일반적으로 PAD4의 억제제인 화학식 (Ia)의 치환된 헤테로시클릭 화합물, 이들 화합물을 제조하는 방법, 이들 화합물을 포함하는 제약 조성물, 및 PAD4 효소 활성과 연관된 질환 또는 장애의 치료에서의 이들 화합물의 용도에 관한 것이다. JPEGpct00983.jpg6696 The disclosure generally relates to substituted heterocyclic compounds of Formula (Ia), which are inhibitors of PAD4, method for prepari...
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| creator | SUBBIAH KARUPPIAH ARUL MOZHI DUNCIA JOHN V SURA MALLIKARJUN REDDY KUMAR CM VIJAYA THANGATHIRUPATHY SRINIVASAN CHERNEY ROBERT J ZHU XIAO PANDA MANORANJAN CUERVO JULIO HERNAN GORMISKY PAUL E GARDNER DANIEL S MIAO GUOBIN ZHU ZHENGDONG ANTROPOW ALYSSA H SELVAKUMAR KUMARAVEL DHAR T. G. MURALI MORAMPUDI OOHA ALAJANGI TIRUPATHI RAO AGARWAL PIYUSH NIU DEQIANG SISTLA RAMESH KUMAR MAHADEVU KRISHNA SELETSKY BORIS M NAIR JALATHI S TINO JOSEPH A PAIDI VENKATRAM REDDY ROSS AUDREY GRAHAM |
| description | 본 개시내용은 일반적으로 PAD4의 억제제인 화학식 (Ia)의 치환된 헤테로시클릭 화합물, 이들 화합물을 제조하는 방법, 이들 화합물을 포함하는 제약 조성물, 및 PAD4 효소 활성과 연관된 질환 또는 장애의 치료에서의 이들 화합물의 용도에 관한 것이다. JPEGpct00983.jpg6696
The disclosure generally relates to substituted heterocyclic compounds of Formula (Ia), which are inhibitors of PAD4, method for preparing these compounds, pharmaceutical compositions comprising these compounds and use of these compounds in the treatment of a disease or a disorder associated with PAD4 enzyme activity. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20220140795A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20220140795A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20220140795A3</originalsourceid><addsrcrecordid>eNrjZFB8O33J29ae1wvnvOme87Zxy-tlaxUCHF1MFN5M2_pmwRwg4mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8d5BRgZGRgaGJgbmlqaOxsSpAgCJJC51</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>헤테로시클릭 PAD4 억제제</title><source>esp@cenet</source><creator>SUBBIAH KARUPPIAH ARUL MOZHI ; DUNCIA JOHN V ; SURA MALLIKARJUN REDDY ; KUMAR CM VIJAYA ; THANGATHIRUPATHY SRINIVASAN ; CHERNEY ROBERT J ; ZHU XIAO ; PANDA MANORANJAN ; CUERVO JULIO HERNAN ; GORMISKY PAUL E ; GARDNER DANIEL S ; MIAO GUOBIN ; ZHU ZHENGDONG ; ANTROPOW ALYSSA H ; SELVAKUMAR KUMARAVEL ; DHAR T. G. MURALI ; MORAMPUDI OOHA ; ALAJANGI TIRUPATHI RAO ; AGARWAL PIYUSH ; NIU DEQIANG ; SISTLA RAMESH KUMAR ; MAHADEVU KRISHNA ; SELETSKY BORIS M ; NAIR JALATHI S ; TINO JOSEPH A ; PAIDI VENKATRAM REDDY ; ROSS AUDREY GRAHAM</creator><creatorcontrib>SUBBIAH KARUPPIAH ARUL MOZHI ; DUNCIA JOHN V ; SURA MALLIKARJUN REDDY ; KUMAR CM VIJAYA ; THANGATHIRUPATHY SRINIVASAN ; CHERNEY ROBERT J ; ZHU XIAO ; PANDA MANORANJAN ; CUERVO JULIO HERNAN ; GORMISKY PAUL E ; GARDNER DANIEL S ; MIAO GUOBIN ; ZHU ZHENGDONG ; ANTROPOW ALYSSA H ; SELVAKUMAR KUMARAVEL ; DHAR T. G. MURALI ; MORAMPUDI OOHA ; ALAJANGI TIRUPATHI RAO ; AGARWAL PIYUSH ; NIU DEQIANG ; SISTLA RAMESH KUMAR ; MAHADEVU KRISHNA ; SELETSKY BORIS M ; NAIR JALATHI S ; TINO JOSEPH A ; PAIDI VENKATRAM REDDY ; ROSS AUDREY GRAHAM</creatorcontrib><description>본 개시내용은 일반적으로 PAD4의 억제제인 화학식 (Ia)의 치환된 헤테로시클릭 화합물, 이들 화합물을 제조하는 방법, 이들 화합물을 포함하는 제약 조성물, 및 PAD4 효소 활성과 연관된 질환 또는 장애의 치료에서의 이들 화합물의 용도에 관한 것이다. JPEGpct00983.jpg6696
The disclosure generally relates to substituted heterocyclic compounds of Formula (Ia), which are inhibitors of PAD4, method for preparing these compounds, pharmaceutical compositions comprising these compounds and use of these compounds in the treatment of a disease or a disorder associated with PAD4 enzyme activity.</description><language>kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221018&DB=EPODOC&CC=KR&NR=20220140795A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221018&DB=EPODOC&CC=KR&NR=20220140795A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SUBBIAH KARUPPIAH ARUL MOZHI</creatorcontrib><creatorcontrib>DUNCIA JOHN V</creatorcontrib><creatorcontrib>SURA MALLIKARJUN REDDY</creatorcontrib><creatorcontrib>KUMAR CM VIJAYA</creatorcontrib><creatorcontrib>THANGATHIRUPATHY SRINIVASAN</creatorcontrib><creatorcontrib>CHERNEY ROBERT J</creatorcontrib><creatorcontrib>ZHU XIAO</creatorcontrib><creatorcontrib>PANDA MANORANJAN</creatorcontrib><creatorcontrib>CUERVO JULIO HERNAN</creatorcontrib><creatorcontrib>GORMISKY PAUL E</creatorcontrib><creatorcontrib>GARDNER DANIEL S</creatorcontrib><creatorcontrib>MIAO GUOBIN</creatorcontrib><creatorcontrib>ZHU ZHENGDONG</creatorcontrib><creatorcontrib>ANTROPOW ALYSSA H</creatorcontrib><creatorcontrib>SELVAKUMAR KUMARAVEL</creatorcontrib><creatorcontrib>DHAR T. G. MURALI</creatorcontrib><creatorcontrib>MORAMPUDI OOHA</creatorcontrib><creatorcontrib>ALAJANGI TIRUPATHI RAO</creatorcontrib><creatorcontrib>AGARWAL PIYUSH</creatorcontrib><creatorcontrib>NIU DEQIANG</creatorcontrib><creatorcontrib>SISTLA RAMESH KUMAR</creatorcontrib><creatorcontrib>MAHADEVU KRISHNA</creatorcontrib><creatorcontrib>SELETSKY BORIS M</creatorcontrib><creatorcontrib>NAIR JALATHI S</creatorcontrib><creatorcontrib>TINO JOSEPH A</creatorcontrib><creatorcontrib>PAIDI VENKATRAM REDDY</creatorcontrib><creatorcontrib>ROSS AUDREY GRAHAM</creatorcontrib><title>헤테로시클릭 PAD4 억제제</title><description>본 개시내용은 일반적으로 PAD4의 억제제인 화학식 (Ia)의 치환된 헤테로시클릭 화합물, 이들 화합물을 제조하는 방법, 이들 화합물을 포함하는 제약 조성물, 및 PAD4 효소 활성과 연관된 질환 또는 장애의 치료에서의 이들 화합물의 용도에 관한 것이다. JPEGpct00983.jpg6696
The disclosure generally relates to substituted heterocyclic compounds of Formula (Ia), which are inhibitors of PAD4, method for preparing these compounds, pharmaceutical compositions comprising these compounds and use of these compounds in the treatment of a disease or a disorder associated with PAD4 enzyme activity.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB8O33J29ae1wvnvOme87Zxy-tlaxUCHF1MFN5M2_pmwRwg4mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8d5BRgZGRgaGJgbmlqaOxsSpAgCJJC51</recordid><startdate>20221018</startdate><enddate>20221018</enddate><creator>SUBBIAH KARUPPIAH ARUL MOZHI</creator><creator>DUNCIA JOHN V</creator><creator>SURA MALLIKARJUN REDDY</creator><creator>KUMAR CM VIJAYA</creator><creator>THANGATHIRUPATHY SRINIVASAN</creator><creator>CHERNEY ROBERT J</creator><creator>ZHU XIAO</creator><creator>PANDA MANORANJAN</creator><creator>CUERVO JULIO HERNAN</creator><creator>GORMISKY PAUL E</creator><creator>GARDNER DANIEL S</creator><creator>MIAO GUOBIN</creator><creator>ZHU ZHENGDONG</creator><creator>ANTROPOW ALYSSA H</creator><creator>SELVAKUMAR KUMARAVEL</creator><creator>DHAR T. 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G. MURALI</au><au>MORAMPUDI OOHA</au><au>ALAJANGI TIRUPATHI RAO</au><au>AGARWAL PIYUSH</au><au>NIU DEQIANG</au><au>SISTLA RAMESH KUMAR</au><au>MAHADEVU KRISHNA</au><au>SELETSKY BORIS M</au><au>NAIR JALATHI S</au><au>TINO JOSEPH A</au><au>PAIDI VENKATRAM REDDY</au><au>ROSS AUDREY GRAHAM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>헤테로시클릭 PAD4 억제제</title><date>2022-10-18</date><risdate>2022</risdate><abstract>본 개시내용은 일반적으로 PAD4의 억제제인 화학식 (Ia)의 치환된 헤테로시클릭 화합물, 이들 화합물을 제조하는 방법, 이들 화합물을 포함하는 제약 조성물, 및 PAD4 효소 활성과 연관된 질환 또는 장애의 치료에서의 이들 화합물의 용도에 관한 것이다. JPEGpct00983.jpg6696
The disclosure generally relates to substituted heterocyclic compounds of Formula (Ia), which are inhibitors of PAD4, method for preparing these compounds, pharmaceutical compositions comprising these compounds and use of these compounds in the treatment of a disease or a disorder associated with PAD4 enzyme activity.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 헤테로시클릭 PAD4 억제제 |
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