Novel electrochemiluminescent co-reactant and electrochemiluminescent system including the same

The present invention relates to a novel electrochemiluminescence (ECL) co-reactant and an ECL system including the same, wherein the ECL co-reactant including a compound represented by the following formula I or a pharmaceutically acceptable salt thereof has a very excellent detection signal and is...

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description The present invention relates to a novel electrochemiluminescence (ECL) co-reactant and an ECL system including the same, wherein the ECL co-reactant including a compound represented by the following formula I or a pharmaceutically acceptable salt thereof has a very excellent detection signal and is capable of improving a voltage application condition during ECL measurement by using specific luminescent species (polycyclic aromatic hydrocarbon compounds, metal complex compounds, quantum dots, or nanoparticles, etc.) as ECL labels, so as to be widely applied to general immunoassay methods, diagnostic devices based thereon, chemical analysis methods and diagnostic devices based thereon. In formula I, R^1 and R^2 may be the same or different and represent one selected from a group consisting of: a hydrogen atom; a halogen atom; a C_1-C_6 straight-chained, branched or cyclic alkyl group; a C_1-C_6 alkoxy group; and a C_1-C_6 haloalkyl group. 본 발명은 신규한 전기화학발광 공반응물 및 이를 포함하는 전기화학발광 시스템에 관한 것으로, 하기 화학식 Ⅰ로 표시되는 화합물, 또는 이의 약제학적으로 허용되는 염을 포함하는 전기화학발광(electrochemiluminescence, ECL) 공반응물(co-reactant)을 특정 발광화학종 (다환 방향족 탄화수소화합물, 금속착화합물, 양자점, 또는 나노입자 등)을 전기화학발광 라벨로 사용하여 전기화학발광 측정 시 검출 신호가 매우 우수하고, 전압 인가 조건의 개선이 가능하여 면역분석법 및 그에 기반한 진단기기, 및 화학분석법과 그에 기반한 진단기기 일반에 널리 적용될 수 있다. [화학식 1] JPEGpat00005.jpg5130 상기 화학식 I에서, 상기 R1 또는 R2는 각각 동일하거나 다를 수 있으며, 수소 원자; 할로겐 원자; C1~C6 직쇄 또는 분쇄 또는 고리형 알킬기; C1~C6 알콕시기; 및 C1~C6 할로알킬기로 이루어진 군에서 선택된 어느 하나를 나타낸다.
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In formula I, R^1 and R^2 may be the same or different and represent one selected from a group consisting of: a hydrogen atom; a halogen atom; a C_1-C_6 straight-chained, branched or cyclic alkyl group; a C_1-C_6 alkoxy group; and a C_1-C_6 haloalkyl group. 본 발명은 신규한 전기화학발광 공반응물 및 이를 포함하는 전기화학발광 시스템에 관한 것으로, 하기 화학식 Ⅰ로 표시되는 화합물, 또는 이의 약제학적으로 허용되는 염을 포함하는 전기화학발광(electrochemiluminescence, ECL) 공반응물(co-reactant)을 특정 발광화학종 (다환 방향족 탄화수소화합물, 금속착화합물, 양자점, 또는 나노입자 등)을 전기화학발광 라벨로 사용하여 전기화학발광 측정 시 검출 신호가 매우 우수하고, 전압 인가 조건의 개선이 가능하여 면역분석법 및 그에 기반한 진단기기, 및 화학분석법과 그에 기반한 진단기기 일반에 널리 적용될 수 있다. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PHYSICS
TESTING
title Novel electrochemiluminescent co-reactant and electrochemiluminescent system including the same
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