SARS-CoV-2 Composition for preventing or treating of SARS-CoV-2 comprising PEGylated Nanoparticle Albumin-Bound Steroidal Ginsenoside Derivatives
The present invention relates to a composition for preventing or treating SARS-CoV-2 containing pegylated albumin-coupled steroid ginsenoside derivative nanoparticles, which can reduce side effects of steroids due to an acute immunosuppressive effect, and eliminates endotoxins such as histones and c...
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| creator | LEE JEE HYUN AHN BYUNG HEE SONG, GYU YONG LEE JAE YOUNG |
| description | The present invention relates to a composition for preventing or treating SARS-CoV-2 containing pegylated albumin-coupled steroid ginsenoside derivative nanoparticles, which can reduce side effects of steroids due to an acute immunosuppressive effect, and eliminates endotoxins such as histones and cytokines in infectious diseases to control organ damage and blood coagulation mechanism caused by cytokine release syndrome or cytokine storm, thereby being able to play an important role in alleviating morbidity and mortality before antiviral drug development in the context of current SARS-CoV-2 epidemic situation.
본 발명은 페길화 알부민 결합 스테로이드 진세노사이드 유도체 나노입자를 포함하는 SARS-CoV-2 예방 또는 치료용 조성물에 관한 것으로, 급성 면역 억제 효과로 인해 스테로이드의 부작용을 줄일 수 있으며, 감염성 질환에서 히스톤 및 사이토 카인과 같은 내 독소를 제거함으로써 사이토카인 방출 증후군 또는 사이토카인 폭풍에 의한 기관 손상과 혈액 응고 메커니즘을 제어하여, 현재 SARS-CoV-2 전염병 상황에서 항 바이러스제 개발 전에 이환율 및 사망률의 개선에 중요한 역할을 할 수 있다. |
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본 발명은 페길화 알부민 결합 스테로이드 진세노사이드 유도체 나노입자를 포함하는 SARS-CoV-2 예방 또는 치료용 조성물에 관한 것으로, 급성 면역 억제 효과로 인해 스테로이드의 부작용을 줄일 수 있으며, 감염성 질환에서 히스톤 및 사이토 카인과 같은 내 독소를 제거함으로써 사이토카인 방출 증후군 또는 사이토카인 폭풍에 의한 기관 손상과 혈액 응고 메커니즘을 제어하여, 현재 SARS-CoV-2 전염병 상황에서 항 바이러스제 개발 전에 이환율 및 사망률의 개선에 중요한 역할을 할 수 있다.</description><language>eng ; kor</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220510&DB=EPODOC&CC=KR&NR=20220059157A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220510&DB=EPODOC&CC=KR&NR=20220059157A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE JEE HYUN</creatorcontrib><creatorcontrib>AHN BYUNG HEE</creatorcontrib><creatorcontrib>SONG, GYU YONG</creatorcontrib><creatorcontrib>LEE JAE YOUNG</creatorcontrib><title>SARS-CoV-2 Composition for preventing or treating of SARS-CoV-2 comprising PEGylated Nanoparticle Albumin-Bound Steroidal Ginsenoside Derivatives</title><description>The present invention relates to a composition for preventing or treating SARS-CoV-2 containing pegylated albumin-coupled steroid ginsenoside derivative nanoparticles, which can reduce side effects of steroids due to an acute immunosuppressive effect, and eliminates endotoxins such as histones and cytokines in infectious diseases to control organ damage and blood coagulation mechanism caused by cytokine release syndrome or cytokine storm, thereby being able to play an important role in alleviating morbidity and mortality before antiviral drug development in the context of current SARS-CoV-2 epidemic situation.
본 발명은 페길화 알부민 결합 스테로이드 진세노사이드 유도체 나노입자를 포함하는 SARS-CoV-2 예방 또는 치료용 조성물에 관한 것으로, 급성 면역 억제 효과로 인해 스테로이드의 부작용을 줄일 수 있으며, 감염성 질환에서 히스톤 및 사이토 카인과 같은 내 독소를 제거함으로써 사이토카인 방출 증후군 또는 사이토카인 폭풍에 의한 기관 손상과 혈액 응고 메커니즘을 제어하여, 현재 SARS-CoV-2 전염병 상황에서 항 바이러스제 개발 전에 이환율 및 사망률의 개선에 중요한 역할을 할 수 있다.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTbsKwkAQTGMh6j8sWAdiRMQyxhcIIkZsw5nbyMJl97g7A36Gf2xEC0urmWFe_ehZZKcizuUSp5BLY8VTIGGoxYF12CIH4ht0KjhUH17DT6nqSo782ziutw-jAmo4KBarXKDKIGTmem-I46XcWUMR0AlpZWBL7JG7Q42wQkdtN9-iH0a9WhmPoy8OovFmfc53MVop0VtVIWMo96c0SdMkmS0ms3k2_S_1ArngTu0</recordid><startdate>20220510</startdate><enddate>20220510</enddate><creator>LEE JEE HYUN</creator><creator>AHN BYUNG HEE</creator><creator>SONG, GYU YONG</creator><creator>LEE JAE YOUNG</creator><scope>EVB</scope></search><sort><creationdate>20220510</creationdate><title>SARS-CoV-2 Composition for preventing or treating of SARS-CoV-2 comprising PEGylated Nanoparticle Albumin-Bound Steroidal Ginsenoside Derivatives</title><author>LEE JEE HYUN ; AHN BYUNG HEE ; SONG, GYU YONG ; LEE JAE YOUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20220059157A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE JEE HYUN</creatorcontrib><creatorcontrib>AHN BYUNG HEE</creatorcontrib><creatorcontrib>SONG, GYU YONG</creatorcontrib><creatorcontrib>LEE JAE YOUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE JEE HYUN</au><au>AHN BYUNG HEE</au><au>SONG, GYU YONG</au><au>LEE JAE YOUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SARS-CoV-2 Composition for preventing or treating of SARS-CoV-2 comprising PEGylated Nanoparticle Albumin-Bound Steroidal Ginsenoside Derivatives</title><date>2022-05-10</date><risdate>2022</risdate><abstract>The present invention relates to a composition for preventing or treating SARS-CoV-2 containing pegylated albumin-coupled steroid ginsenoside derivative nanoparticles, which can reduce side effects of steroids due to an acute immunosuppressive effect, and eliminates endotoxins such as histones and cytokines in infectious diseases to control organ damage and blood coagulation mechanism caused by cytokine release syndrome or cytokine storm, thereby being able to play an important role in alleviating morbidity and mortality before antiviral drug development in the context of current SARS-CoV-2 epidemic situation.
본 발명은 페길화 알부민 결합 스테로이드 진세노사이드 유도체 나노입자를 포함하는 SARS-CoV-2 예방 또는 치료용 조성물에 관한 것으로, 급성 면역 억제 효과로 인해 스테로이드의 부작용을 줄일 수 있으며, 감염성 질환에서 히스톤 및 사이토 카인과 같은 내 독소를 제거함으로써 사이토카인 방출 증후군 또는 사이토카인 폭풍에 의한 기관 손상과 혈액 응고 메커니즘을 제어하여, 현재 SARS-CoV-2 전염병 상황에서 항 바이러스제 개발 전에 이환율 및 사망률의 개선에 중요한 역할을 할 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| title | SARS-CoV-2 Composition for preventing or treating of SARS-CoV-2 comprising PEGylated Nanoparticle Albumin-Bound Steroidal Ginsenoside Derivatives |
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