포도당 민감성 인슐린 유도체
본 발명은 신규 인슐린 유도체 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이의 용도에 관한 것이다. 인슐린 유도체는 포도당에 민감하고 포도당에 민감한 알부민 결합을 나타낸다. 본 발명은 또한 신규 중간체에 관한 것이다. 결과적으로, 본 발명은 본 발명의 인슐린 유도체를 포함하는 약학적 조성물 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이러한 조성물의 용도를 제공한다. The present invention relates to novel insulin derivatives and their use...
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| creator | DROZ LADISLAV SNAJDR IVAN KRUSE THOMAS THØGERSEN HENNING HAVRANEK MIROSLAV SAUERBERG PER HOEG JENSEN THOMAS KOTEK VLADISLAV STENGL MILAN CLO EMILIANO SPETZLER JANE MUNZEL MARTIN WERNER BORCHSENIUS BEHRENS CARSTEN BALSANEK VOJTECH VANOVA HANA SENSFUSS ULRICH DROBNAKOVA ZUZANA HJØRRINGGAARD CLAUDIA ULRICH |
| description | 본 발명은 신규 인슐린 유도체 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이의 용도에 관한 것이다. 인슐린 유도체는 포도당에 민감하고 포도당에 민감한 알부민 결합을 나타낸다. 본 발명은 또한 신규 중간체에 관한 것이다. 결과적으로, 본 발명은 본 발명의 인슐린 유도체를 포함하는 약학적 조성물 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이러한 조성물의 용도를 제공한다.
The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention also relates to novel intermediates. Finally, the invention provides a pharmaceutical composition comprising the insulin derivatives of the invention and the use of such a composition in the treatment or prevention of medical conditions relating to diabetes. |
| format | Patent |
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The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention also relates to novel intermediates. Finally, the invention provides a pharmaceutical composition comprising the insulin derivatives of the invention and the use of such a composition in the treatment or prevention of medical conditions relating to diabetes.</description><language>kor</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211207&DB=EPODOC&CC=KR&NR=20210148143A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211207&DB=EPODOC&CC=KR&NR=20210148143A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DROZ LADISLAV</creatorcontrib><creatorcontrib>SNAJDR IVAN</creatorcontrib><creatorcontrib>KRUSE THOMAS</creatorcontrib><creatorcontrib>THØGERSEN HENNING</creatorcontrib><creatorcontrib>HAVRANEK MIROSLAV</creatorcontrib><creatorcontrib>SAUERBERG PER</creatorcontrib><creatorcontrib>HOEG JENSEN THOMAS</creatorcontrib><creatorcontrib>KOTEK VLADISLAV</creatorcontrib><creatorcontrib>STENGL MILAN</creatorcontrib><creatorcontrib>CLO EMILIANO</creatorcontrib><creatorcontrib>SPETZLER JANE</creatorcontrib><creatorcontrib>MUNZEL MARTIN WERNER BORCHSENIUS</creatorcontrib><creatorcontrib>BEHRENS CARSTEN</creatorcontrib><creatorcontrib>BALSANEK VOJTECH</creatorcontrib><creatorcontrib>VANOVA HANA</creatorcontrib><creatorcontrib>SENSFUSS ULRICH</creatorcontrib><creatorcontrib>DROBNAKOVA ZUZANA</creatorcontrib><creatorcontrib>HJØRRINGGAARD CLAUDIA ULRICH</creatorcontrib><title>포도당 민감성 인슐린 유도체</title><description>본 발명은 신규 인슐린 유도체 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이의 용도에 관한 것이다. 인슐린 유도체는 포도당에 민감하고 포도당에 민감한 알부민 결합을 나타낸다. 본 발명은 또한 신규 중간체에 관한 것이다. 결과적으로, 본 발명은 본 발명의 인슐린 유도체를 포함하는 약학적 조성물 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이러한 조성물의 용도를 제공한다.
The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention also relates to novel intermediates. Finally, the invention provides a pharmaceutical composition comprising the insulin derivatives of the invention and the use of such a composition in the treatment or prevention of medical conditions relating to diabetes.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB_27_mdX_L6-6dCq_X73m1YcKblo0Kb-bueNM14fWyDQpv5iwAyr7ZtIWHgTUtMac4lRdKczMou7mGOHvophbkx6cWFyQmp-allsR7BxkZGBkaGJpYGJoYOxoTpwoARMY0NA</recordid><startdate>20211207</startdate><enddate>20211207</enddate><creator>DROZ LADISLAV</creator><creator>SNAJDR IVAN</creator><creator>KRUSE THOMAS</creator><creator>THØGERSEN HENNING</creator><creator>HAVRANEK MIROSLAV</creator><creator>SAUERBERG PER</creator><creator>HOEG JENSEN THOMAS</creator><creator>KOTEK VLADISLAV</creator><creator>STENGL MILAN</creator><creator>CLO EMILIANO</creator><creator>SPETZLER JANE</creator><creator>MUNZEL MARTIN WERNER BORCHSENIUS</creator><creator>BEHRENS CARSTEN</creator><creator>BALSANEK VOJTECH</creator><creator>VANOVA HANA</creator><creator>SENSFUSS ULRICH</creator><creator>DROBNAKOVA ZUZANA</creator><creator>HJØRRINGGAARD CLAUDIA ULRICH</creator><scope>EVB</scope></search><sort><creationdate>20211207</creationdate><title>포도당 민감성 인슐린 유도체</title><author>DROZ LADISLAV ; SNAJDR IVAN ; KRUSE THOMAS ; THØGERSEN HENNING ; HAVRANEK MIROSLAV ; SAUERBERG PER ; HOEG JENSEN THOMAS ; KOTEK VLADISLAV ; STENGL MILAN ; CLO EMILIANO ; SPETZLER JANE ; MUNZEL MARTIN WERNER BORCHSENIUS ; BEHRENS CARSTEN ; BALSANEK VOJTECH ; VANOVA HANA ; SENSFUSS ULRICH ; DROBNAKOVA ZUZANA ; HJØRRINGGAARD CLAUDIA ULRICH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20210148143A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DROZ LADISLAV</creatorcontrib><creatorcontrib>SNAJDR IVAN</creatorcontrib><creatorcontrib>KRUSE THOMAS</creatorcontrib><creatorcontrib>THØGERSEN HENNING</creatorcontrib><creatorcontrib>HAVRANEK MIROSLAV</creatorcontrib><creatorcontrib>SAUERBERG PER</creatorcontrib><creatorcontrib>HOEG JENSEN THOMAS</creatorcontrib><creatorcontrib>KOTEK VLADISLAV</creatorcontrib><creatorcontrib>STENGL MILAN</creatorcontrib><creatorcontrib>CLO EMILIANO</creatorcontrib><creatorcontrib>SPETZLER JANE</creatorcontrib><creatorcontrib>MUNZEL MARTIN WERNER BORCHSENIUS</creatorcontrib><creatorcontrib>BEHRENS CARSTEN</creatorcontrib><creatorcontrib>BALSANEK VOJTECH</creatorcontrib><creatorcontrib>VANOVA HANA</creatorcontrib><creatorcontrib>SENSFUSS ULRICH</creatorcontrib><creatorcontrib>DROBNAKOVA ZUZANA</creatorcontrib><creatorcontrib>HJØRRINGGAARD CLAUDIA ULRICH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DROZ LADISLAV</au><au>SNAJDR IVAN</au><au>KRUSE THOMAS</au><au>THØGERSEN HENNING</au><au>HAVRANEK MIROSLAV</au><au>SAUERBERG PER</au><au>HOEG JENSEN THOMAS</au><au>KOTEK VLADISLAV</au><au>STENGL MILAN</au><au>CLO EMILIANO</au><au>SPETZLER JANE</au><au>MUNZEL MARTIN WERNER BORCHSENIUS</au><au>BEHRENS CARSTEN</au><au>BALSANEK VOJTECH</au><au>VANOVA HANA</au><au>SENSFUSS ULRICH</au><au>DROBNAKOVA ZUZANA</au><au>HJØRRINGGAARD CLAUDIA ULRICH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>포도당 민감성 인슐린 유도체</title><date>2021-12-07</date><risdate>2021</risdate><abstract>본 발명은 신규 인슐린 유도체 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이의 용도에 관한 것이다. 인슐린 유도체는 포도당에 민감하고 포도당에 민감한 알부민 결합을 나타낸다. 본 발명은 또한 신규 중간체에 관한 것이다. 결과적으로, 본 발명은 본 발명의 인슐린 유도체를 포함하는 약학적 조성물 및 당뇨병과 관련된 의학적 병태의 치료 또는 예방에 있어서의 이러한 조성물의 용도를 제공한다.
The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention also relates to novel intermediates. Finally, the invention provides a pharmaceutical composition comprising the insulin derivatives of the invention and the use of such a composition in the treatment or prevention of medical conditions relating to diabetes.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 포도당 민감성 인슐린 유도체 |
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