PLK1 Vanillin derivative compounds inducing selective degradation of PLK1

The present invention relates to novel compounds that induce selective degradation of PLK1, and more particularly, to a bifunctional compound in which a PLK1 binding moiety and an E3 ubiquitin ligase binding moiety are linked by a chemical linker. The present invention provides the compound, a metho...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	KEUM YOUNG KANG, HYE GUK RYU, HWA JIN LEE, SEONG HOON KIM, SI WOO CHOI, JI HOON RYU, IM SUK MIN, SAN HA SON, SOO HEE RYU, BOAS NAM
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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