A Composition for inhibiting -lactamase for the control of multiple drug resistant Staphylococcus aureus

The present invention relates to a composition for inhibiting beta-lactamase comprising at least one extract selected from a group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera as an active ingredient, and an antib...

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Hauptverfasser: LEE JONG WON, JEON GI BEOM, AHN JU HEE
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JEON GI BEOM
AHN JU HEE
description The present invention relates to a composition for inhibiting beta-lactamase comprising at least one extract selected from a group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera as an active ingredient, and an antibacterial composition for Staphylococcus aureus containing, as an active ingredient, a beta-lactam antibiotic and one or more extracts selected from the group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera. The natural extract of the present invention can be used as a new adjuvant to increase the antibacterial effect of piperacillin, a penicillin family, and can be used to inhibit the resistance mechanism of microorganisms as an inhibitor capable of inhibiting β-lactamase, an enzyme that degrades β-lactam ring. 본 발명은 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물을 유효성분으로 포함하는 베타-락타메이즈 저해용 조성물, 및 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물과 베타-락탐계 항생제를 유효성분으로 포함하는 Staphylococcus aureus에 대한 항균용 조성물에 관한 것이다.본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가 시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다. 본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다.
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The natural extract of the present invention can be used as a new adjuvant to increase the antibacterial effect of piperacillin, a penicillin family, and can be used to inhibit the resistance mechanism of microorganisms as an inhibitor capable of inhibiting β-lactamase, an enzyme that degrades β-lactam ring. 본 발명은 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물을 유효성분으로 포함하는 베타-락타메이즈 저해용 조성물, 및 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물과 베타-락탐계 항생제를 유효성분으로 포함하는 Staphylococcus aureus에 대한 항균용 조성물에 관한 것이다.본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가 시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다. 본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다.</description><language>eng ; kor</language><subject>FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210526&amp;DB=EPODOC&amp;CC=KR&amp;NR=20210060154A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210526&amp;DB=EPODOC&amp;CC=KR&amp;NR=20210060154A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE JONG WON</creatorcontrib><creatorcontrib>JEON GI BEOM</creatorcontrib><creatorcontrib>AHN JU HEE</creatorcontrib><title>A Composition for inhibiting -lactamase for the control of multiple drug resistant Staphylococcus aureus</title><description>The present invention relates to a composition for inhibiting beta-lactamase comprising at least one extract selected from a group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera as an active ingredient, and an antibacterial composition for Staphylococcus aureus containing, as an active ingredient, a beta-lactam antibiotic and one or more extracts selected from the group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera. The natural extract of the present invention can be used as a new adjuvant to increase the antibacterial effect of piperacillin, a penicillin family, and can be used to inhibit the resistance mechanism of microorganisms as an inhibitor capable of inhibiting β-lactamase, an enzyme that degrades β-lactam ring. 본 발명은 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물을 유효성분으로 포함하는 베타-락타메이즈 저해용 조성물, 및 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물과 베타-락탐계 항생제를 유효성분으로 포함하는 Staphylococcus aureus에 대한 항균용 조성물에 관한 것이다.본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가 시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다. 본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다.</description><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNissKwjAQAHvxIOo_LHgupL7upSiCN_Ve1rhtAmk2ZDcH_14RP8DTMMzMK9dCx1Ni8eo5wsAZfHT-8dE4Qh3QKk4o9C3qCCxHzRyAB5hKUJ8CwTOXETKJF8WocFNM7hXYsrVFAEumIstqNmAQWv24qNan470715S4J0loKZL2l-vGbBpjDqbZ79rtf9cbHPhBkA</recordid><startdate>20210526</startdate><enddate>20210526</enddate><creator>LEE JONG WON</creator><creator>JEON GI BEOM</creator><creator>AHN JU HEE</creator><scope>EVB</scope></search><sort><creationdate>20210526</creationdate><title>A Composition for inhibiting -lactamase for the control of multiple drug resistant Staphylococcus aureus</title><author>LEE JONG WON ; JEON GI BEOM ; AHN JU HEE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20210060154A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2021</creationdate><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE JONG WON</creatorcontrib><creatorcontrib>JEON GI BEOM</creatorcontrib><creatorcontrib>AHN JU HEE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE JONG WON</au><au>JEON GI BEOM</au><au>AHN JU HEE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A Composition for inhibiting -lactamase for the control of multiple drug resistant Staphylococcus aureus</title><date>2021-05-26</date><risdate>2021</risdate><abstract>The present invention relates to a composition for inhibiting beta-lactamase comprising at least one extract selected from a group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera as an active ingredient, and an antibacterial composition for Staphylococcus aureus containing, as an active ingredient, a beta-lactam antibiotic and one or more extracts selected from the group consisting of extracts of Cleyera japonica, Euphorbia helioscopia, wild rose, Euscaphis japonica, Carpinus laxiflora, and Oenothera. The natural extract of the present invention can be used as a new adjuvant to increase the antibacterial effect of piperacillin, a penicillin family, and can be used to inhibit the resistance mechanism of microorganisms as an inhibitor capable of inhibiting β-lactamase, an enzyme that degrades β-lactam ring. 본 발명은 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물을 유효성분으로 포함하는 베타-락타메이즈 저해용 조성물, 및 비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및 왕달맞이꽃 추출물로 구성된 군으로부터 선택된 하나 이상의 추출물과 베타-락탐계 항생제를 유효성분으로 포함하는 Staphylococcus aureus에 대한 항균용 조성물에 관한 것이다.본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가 시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다. 본 발명의 천연추출물이 페니실린 계열인 piperacillin의 항균효과를 증가시키는 새로운 보조제로서 사용될 수 있으며, β-lactam ring 분해 효소인 β-lactamase을 억제할 수 있는 inhibitor로서 미생물의 내성기전 저해에 사용될 수 있다.</abstract><oa>free_for_read</oa></addata></record>
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subjects FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title A Composition for inhibiting -lactamase for the control of multiple drug resistant Staphylococcus aureus
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