PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS

본 발명은 나트륨 채널의 억제제로서 유용한 화학식 I 및 화학식 I'의 피리돈 아미드 화합물 또는 이의 약제학적으로 허용되는 염에 관한 것이다. 또한, 본 발명은 본 발명의 화합물을 포함하는 약제학적으로 허용되는 조성물, 및 통증을 포함하는 각종 장애들의 치료에서의 상기 조성물의 사용 방법을 제공한다. 화학식 I JPEGpat00283.jpg3044 화학식 I' JPEGpat00284.jpg3043 The invention relates to pyridone amide compounds of formula I an...

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Hauptverfasser: HADIDA RUAH SARA SABINA, BEAR BRIAN RICHARD, JOHNSON JAMES PHILIP, ARUMUGAM VIJAYALAKSMI, ANDERSON COREY, ASGIAN IULIANA LUCI, TERMIN ANDREAS P
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creator HADIDA RUAH SARA SABINA
BEAR BRIAN RICHARD
JOHNSON JAMES PHILIP
ARUMUGAM VIJAYALAKSMI
ANDERSON COREY
ASGIAN IULIANA LUCI
TERMIN ANDREAS P
description 본 발명은 나트륨 채널의 억제제로서 유용한 화학식 I 및 화학식 I'의 피리돈 아미드 화합물 또는 이의 약제학적으로 허용되는 염에 관한 것이다. 또한, 본 발명은 본 발명의 화합물을 포함하는 약제학적으로 허용되는 조성물, 및 통증을 포함하는 각종 장애들의 치료에서의 상기 조성물의 사용 방법을 제공한다. 화학식 I JPEGpat00283.jpg3044 화학식 I' JPEGpat00284.jpg3043 The invention relates to pyridone amide compounds of formula I and I'or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels:The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS
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