5--벤조[D]옥사졸-2(3H)-온의 푸마레이트 염

5-((5-메틸-2-((3,4,5-트리메틸페닐)아미노)피리미딘-4-일)아미노)-벤조[d]옥사졸-2(3H)-온 (화합물 (I)의 푸마레이트 염, 특히 헤미-푸마레이트 염, 그와 같은 염을 포함하는 조성물, 및 그와 같은 염, 특히 화합물 (I) 헤미-푸마레이트 염의 제조 방법이 기재되어 있다. 상기 염은 JAK 경로의 조절 또는 JAK 키나제 특히 JAK1의 억제를 수반하는 병태 예컨대 천식 및 CORD의 치료에 유용하다. JPEGpct00007.jpg4453 화합물 (I) A fumarate salt, in particular th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SCHULZ HAKAN, SMITH REED WARREN
Format: Patent
Sprache:kor
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator SCHULZ HAKAN
SMITH REED WARREN
description 5-((5-메틸-2-((3,4,5-트리메틸페닐)아미노)피리미딘-4-일)아미노)-벤조[d]옥사졸-2(3H)-온 (화합물 (I)의 푸마레이트 염, 특히 헤미-푸마레이트 염, 그와 같은 염을 포함하는 조성물, 및 그와 같은 염, 특히 화합물 (I) 헤미-푸마레이트 염의 제조 방법이 기재되어 있다. 상기 염은 JAK 경로의 조절 또는 JAK 키나제 특히 JAK1의 억제를 수반하는 병태 예컨대 천식 및 CORD의 치료에 유용하다. JPEGpct00007.jpg4453 화합물 (I) A fumarate salt, in particular the hemi-fumarate salt, of 5-((5-methyl-2-((3,4,5-trimethylphenyl)amino)pyrimidin-4-yl)amino)-benzo[d]oxazol-2(3H)-one (Compound (I), compositions comprising such a salt, and processes for the manufacture of such a salt, in particular Compound (I) hemi-fumarate salt are described. The salt is useful for the treatment of conditions such as asthma and COPD, involving modulation of the JAK pathway or inhibition of JAK kinases particularly JAK1.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20210012006A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20210012006A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20210012006A3</originalsourceid><addsrcrecordid>eNrjZDAz1dV9vWnJm4Ubol1i38xY-qZpzZuFO3SNNIw9NHXfzFjxZu4MhbcTd7xe3vF6QcebuVvedu1QeDN9Dw8Da1piTnEqL5TmZlB2cw1x9tBNLciPTy0uSExOzUstifcOMjIwMjQwMDQyMDBzNCZOFQBOhDlZ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>5--벤조[D]옥사졸-2(3H)-온의 푸마레이트 염</title><source>esp@cenet</source><creator>SCHULZ HAKAN ; SMITH REED WARREN</creator><creatorcontrib>SCHULZ HAKAN ; SMITH REED WARREN</creatorcontrib><description>5-((5-메틸-2-((3,4,5-트리메틸페닐)아미노)피리미딘-4-일)아미노)-벤조[d]옥사졸-2(3H)-온 (화합물 (I)의 푸마레이트 염, 특히 헤미-푸마레이트 염, 그와 같은 염을 포함하는 조성물, 및 그와 같은 염, 특히 화합물 (I) 헤미-푸마레이트 염의 제조 방법이 기재되어 있다. 상기 염은 JAK 경로의 조절 또는 JAK 키나제 특히 JAK1의 억제를 수반하는 병태 예컨대 천식 및 CORD의 치료에 유용하다. JPEGpct00007.jpg4453 화합물 (I) A fumarate salt, in particular the hemi-fumarate salt, of 5-((5-methyl-2-((3,4,5-trimethylphenyl)amino)pyrimidin-4-yl)amino)-benzo[d]oxazol-2(3H)-one (Compound (I), compositions comprising such a salt, and processes for the manufacture of such a salt, in particular Compound (I) hemi-fumarate salt are described. The salt is useful for the treatment of conditions such as asthma and COPD, involving modulation of the JAK pathway or inhibition of JAK kinases particularly JAK1.</description><language>kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210202&amp;DB=EPODOC&amp;CC=KR&amp;NR=20210012006A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210202&amp;DB=EPODOC&amp;CC=KR&amp;NR=20210012006A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SCHULZ HAKAN</creatorcontrib><creatorcontrib>SMITH REED WARREN</creatorcontrib><title>5--벤조[D]옥사졸-2(3H)-온의 푸마레이트 염</title><description>5-((5-메틸-2-((3,4,5-트리메틸페닐)아미노)피리미딘-4-일)아미노)-벤조[d]옥사졸-2(3H)-온 (화합물 (I)의 푸마레이트 염, 특히 헤미-푸마레이트 염, 그와 같은 염을 포함하는 조성물, 및 그와 같은 염, 특히 화합물 (I) 헤미-푸마레이트 염의 제조 방법이 기재되어 있다. 상기 염은 JAK 경로의 조절 또는 JAK 키나제 특히 JAK1의 억제를 수반하는 병태 예컨대 천식 및 CORD의 치료에 유용하다. JPEGpct00007.jpg4453 화합물 (I) A fumarate salt, in particular the hemi-fumarate salt, of 5-((5-methyl-2-((3,4,5-trimethylphenyl)amino)pyrimidin-4-yl)amino)-benzo[d]oxazol-2(3H)-one (Compound (I), compositions comprising such a salt, and processes for the manufacture of such a salt, in particular Compound (I) hemi-fumarate salt are described. The salt is useful for the treatment of conditions such as asthma and COPD, involving modulation of the JAK pathway or inhibition of JAK kinases particularly JAK1.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAz1dV9vWnJm4Ubol1i38xY-qZpzZuFO3SNNIw9NHXfzFjxZu4MhbcTd7xe3vF6QcebuVvedu1QeDN9Dw8Da1piTnEqL5TmZlB2cw1x9tBNLciPTy0uSExOzUstifcOMjIwMjQwMDQyMDBzNCZOFQBOhDlZ</recordid><startdate>20210202</startdate><enddate>20210202</enddate><creator>SCHULZ HAKAN</creator><creator>SMITH REED WARREN</creator><scope>EVB</scope></search><sort><creationdate>20210202</creationdate><title>5--벤조[D]옥사졸-2(3H)-온의 푸마레이트 염</title><author>SCHULZ HAKAN ; SMITH REED WARREN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20210012006A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SCHULZ HAKAN</creatorcontrib><creatorcontrib>SMITH REED WARREN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SCHULZ HAKAN</au><au>SMITH REED WARREN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>5--벤조[D]옥사졸-2(3H)-온의 푸마레이트 염</title><date>2021-02-02</date><risdate>2021</risdate><abstract>5-((5-메틸-2-((3,4,5-트리메틸페닐)아미노)피리미딘-4-일)아미노)-벤조[d]옥사졸-2(3H)-온 (화합물 (I)의 푸마레이트 염, 특히 헤미-푸마레이트 염, 그와 같은 염을 포함하는 조성물, 및 그와 같은 염, 특히 화합물 (I) 헤미-푸마레이트 염의 제조 방법이 기재되어 있다. 상기 염은 JAK 경로의 조절 또는 JAK 키나제 특히 JAK1의 억제를 수반하는 병태 예컨대 천식 및 CORD의 치료에 유용하다. JPEGpct00007.jpg4453 화합물 (I) A fumarate salt, in particular the hemi-fumarate salt, of 5-((5-methyl-2-((3,4,5-trimethylphenyl)amino)pyrimidin-4-yl)amino)-benzo[d]oxazol-2(3H)-one (Compound (I), compositions comprising such a salt, and processes for the manufacture of such a salt, in particular Compound (I) hemi-fumarate salt are described. The salt is useful for the treatment of conditions such as asthma and COPD, involving modulation of the JAK pathway or inhibition of JAK kinases particularly JAK1.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language kor
recordid cdi_epo_espacenet_KR20210012006A
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 5--벤조[D]옥사졸-2(3H)-온의 푸마레이트 염
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T16%3A33%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SCHULZ%20HAKAN&rft.date=2021-02-02&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EKR20210012006A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true