핵산 색인 기술

예를 들면, 서열분석과 함께 사용하기 위한, 핵산의 색인을 위한 기술이 본 명세서에 나타난다. 기술은 색인된 핵산 단편을 개별적인 샘플로부터 생성하는 것을 포함하고, 이로써 핵산 단편의 각각의 색인 부위로 혼입된 색인 서열은 색인 서열과 구별 가능한 복수로부터 선택되고, 따라서 생성된 핵산 단편의 집단은 복수로부터의 각각의 색인 서열을 나타낸다. 이러한 방식으로, 단일 샘플로부터 생성된 색인된 핵산 단편은 낮은 서열 다양성과 연관된 색인 판독물 오류로 인한 잘못된 할당을 감소시키는 다양한 색인 서열의 혼합물에 의해 색인된다. Pre...

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Hauptverfasser: VIECELI JOHN S, KELLEY RYAN MATTHEW
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KELLEY RYAN MATTHEW
description 예를 들면, 서열분석과 함께 사용하기 위한, 핵산의 색인을 위한 기술이 본 명세서에 나타난다. 기술은 색인된 핵산 단편을 개별적인 샘플로부터 생성하는 것을 포함하고, 이로써 핵산 단편의 각각의 색인 부위로 혼입된 색인 서열은 색인 서열과 구별 가능한 복수로부터 선택되고, 따라서 생성된 핵산 단편의 집단은 복수로부터의 각각의 색인 서열을 나타낸다. 이러한 방식으로, 단일 샘플로부터 생성된 색인된 핵산 단편은 낮은 서열 다양성과 연관된 색인 판독물 오류로 인한 잘못된 할당을 감소시키는 다양한 색인 서열의 혼합물에 의해 색인된다. Presented herein are techniques for indexing of nucleic acid, e.g., for use in conjunction with sequencing. The techniques include generating indexed nucleic acid fragments from an individual sample, whereby the index sequence incorporated into each index site of the nucleic acid fragment is selected from a plurality of distinguishable of index sequences and such that the population of generated nucleic acid fragments represents each index sequence from the plurality. In this manner, the generated indexed nucleic acid fragments from a single sample are indexed with a diverse mix of index sequences that reduce misassignment due to index read errors associated with low sequence diversity.
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Presented herein are techniques for indexing of nucleic acid, e.g., for use in conjunction with sequencing. The techniques include generating indexed nucleic acid fragments from an individual sample, whereby the index sequence incorporated into each index site of the nucleic acid fragment is selected from a plurality of distinguishable of index sequences and such that the population of generated nucleic acid fragments represents each index sequence from the plurality. 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Presented herein are techniques for indexing of nucleic acid, e.g., for use in conjunction with sequencing. The techniques include generating indexed nucleic acid fragments from an individual sample, whereby the index sequence incorporated into each index site of the nucleic acid fragment is selected from a plurality of distinguishable of index sequences and such that the population of generated nucleic acid fragments represents each index sequence from the plurality. In this manner, the generated indexed nucleic acid fragments from a single sample are indexed with a diverse mix of index sequences that reduce misassignment due to index read errors associated with low sequence diversity.</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title 핵산 색인 기술
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