Fluorescence compounds complex nanoparticles comprising the same and preparation method thereof

The present invention relates to a fluorescent compound, a composite nanoparticle comprising the same, and a production method thereof. The fluorescent compound according to the present invention is not accumulated when administrating the fluorescent compound into the body, has excellent fluorescenc...

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Bibliographische Detailangaben
Hauptverfasser:	JEONG EUNAE, JANG SU JUNG, YOON HYUNG JUN, JIN WOO PARK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	ADHESIVES CHEMISTRY DYES HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEDICAL OR VETERINARY SCIENCE METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS NANOTECHNOLOGY NATURAL RESINS PAINTS PERFORMING OPERATIONS POLISHES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention relates to a fluorescent compound, a composite nanoparticle comprising the same, and a production method thereof. The fluorescent compound according to the present invention is not accumulated when administrating the fluorescent compound into the body, has excellent fluorescence intensity, is easy to dye and image in the body even in a small amount of use compared to conventional dyes, and thus is economically available. The fluorescent compound-bile acid-chitosan nanoparticles according to the present invention show excellent cancer targeting ability. 본 발명은 형광 화합물, 이를 포함하는 복합체 나노입자, 및 이의 제조방법에 관한 것이다. 본 발명에 따른 형광 화합물은 체내에 투여 시 축적되지 않으면서도 형광 강도가 우수하여 종래의 염료에 비하여 소량의 사용에도 염색 및 체내 영상화가 용이하여 경제적으로 이용이 가능하다. 뿐만 아니라, 본 발명에 따른 형광화합물-담즙산-키토산 나노입자는 우수한 암 타겟능을 보인다.