5-HT7 Arylpyrazolylpiperazine or diazepane derivatives acting as 5-HT7 receptor ligands and pharmaceutical composition for treating or preventing central nervous system diseases
The present invention relates to aryl pyrazolyl piperazine represented by structural formula 1 or derivatives of aryl pyrazolyl piperazine and a pharmaceutically acceptable salt thereof. Accordingly, aryl pyrazolyl piperazine or derivatives of aryl pyrazolyl piperazine and the pharmaceutically accep...
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| Format: | Patent |
| Sprache: | eng ; kor |
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| Zusammenfassung: | The present invention relates to aryl pyrazolyl piperazine represented by structural formula 1 or derivatives of aryl pyrazolyl piperazine and a pharmaceutically acceptable salt thereof. Accordingly, aryl pyrazolyl piperazine or derivatives of aryl pyrazolyl piperazine and the pharmaceutically acceptable salt thereof according to the present invention exhibit excellent binding affinity to a 5-HT7 serotonin receptor and can exhibit an effect for treating central nervous system diseases.
본 발명은 하기 구조식 1로 표시되는 아릴피라졸릴피페라진 또는 아릴피라졸릴다이아제페인의 유도체 및 약제학적으로 허용 가능한 이의 염에 관한 것이다. 이에 따라, 본 발명의 아릴피라졸릴피페라진 또는 아릴피라졸릴다이아제페인의 유도체 및 약제학적으로 허용 가능한 이의 염은 5-HT세로토닌 수용체에 대하여 우수한 결합친화력을 나타내며, 중추신경계 질환 치료에 효과를 나타낼 수 있다. [구조식 1] |
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