Peptide Nucleic Acid Complex with Increased Cell Permeability and pharmaceutical composition comprising the same
The present invention relates to a nucleic acid complex with a new structure capable of introducing bioactive nucleic acid into cells, a composition for the treatment and diagnosis of diseases including the same, and an expression control method of a target gene using the same. More specifically, th...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; kor |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KIM HYE JOO PARK HEE KYUNG JEO GOONHO HUR DEOKHWE YU JI YEON BATOCHIR CHINBAYAR |
| description | The present invention relates to a nucleic acid complex with a new structure capable of introducing bioactive nucleic acid into cells, a composition for the treatment and diagnosis of diseases including the same, and an expression control method of a target gene using the same. More specifically, the present invention relates to: a nucleic acid complex where bioactive nucleic acid and carrier peptide nucleic acid modified to generally have a positive charge are complementarily combined to each other; a composition for the treatment and diagnosis of diseases including the same; and an expression control method of a target gene using the same.
본 발명은 생활성 핵산을 세포내에 도입할 수 있는 새로운 구조의 핵산 복합체, 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것으로, 더욱 자세하게는, 생활성 핵산과 전체적으로 양전하를 가지도록 변형된 캐리어 펩티드 핵산(Carrier Peptide Nucleic Acid)이 상보적으로 결합된 핵산 복합체 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것이다. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20180100523A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20180100523A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20180100523A3</originalsourceid><addsrcrecordid>eNqNjEEKwjAURLtxIeodPrgW0orgthRFEaSI-_JNR_shSUOSot7eIh7A1QyPeTPNfA2fpAWdB20gmkotLVW99QYvekrq6Oh0AEeMGMZQjWDBNzGS3sSuJd9xsKwxJNFsSI9uHyVJ7749SBT3oNSBIlvMs8mdTcTil7Nsud9dq8MKvm8Q_XjkkJrTpVD5VuVKbYp1uf5v9QEz50QT</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Peptide Nucleic Acid Complex with Increased Cell Permeability and pharmaceutical composition comprising the same</title><source>esp@cenet</source><creator>KIM HYE JOO ; PARK HEE KYUNG ; JEO GOONHO ; HUR DEOKHWE ; YU JI YEON ; BATOCHIR CHINBAYAR</creator><creatorcontrib>KIM HYE JOO ; PARK HEE KYUNG ; JEO GOONHO ; HUR DEOKHWE ; YU JI YEON ; BATOCHIR CHINBAYAR</creatorcontrib><description>The present invention relates to a nucleic acid complex with a new structure capable of introducing bioactive nucleic acid into cells, a composition for the treatment and diagnosis of diseases including the same, and an expression control method of a target gene using the same. More specifically, the present invention relates to: a nucleic acid complex where bioactive nucleic acid and carrier peptide nucleic acid modified to generally have a positive charge are complementarily combined to each other; a composition for the treatment and diagnosis of diseases including the same; and an expression control method of a target gene using the same.
본 발명은 생활성 핵산을 세포내에 도입할 수 있는 새로운 구조의 핵산 복합체, 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것으로, 더욱 자세하게는, 생활성 핵산과 전체적으로 양전하를 가지도록 변형된 캐리어 펩티드 핵산(Carrier Peptide Nucleic Acid)이 상보적으로 결합된 핵산 복합체 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것이다.</description><language>eng ; kor</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180911&DB=EPODOC&CC=KR&NR=20180100523A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180911&DB=EPODOC&CC=KR&NR=20180100523A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM HYE JOO</creatorcontrib><creatorcontrib>PARK HEE KYUNG</creatorcontrib><creatorcontrib>JEO GOONHO</creatorcontrib><creatorcontrib>HUR DEOKHWE</creatorcontrib><creatorcontrib>YU JI YEON</creatorcontrib><creatorcontrib>BATOCHIR CHINBAYAR</creatorcontrib><title>Peptide Nucleic Acid Complex with Increased Cell Permeability and pharmaceutical composition comprising the same</title><description>The present invention relates to a nucleic acid complex with a new structure capable of introducing bioactive nucleic acid into cells, a composition for the treatment and diagnosis of diseases including the same, and an expression control method of a target gene using the same. More specifically, the present invention relates to: a nucleic acid complex where bioactive nucleic acid and carrier peptide nucleic acid modified to generally have a positive charge are complementarily combined to each other; a composition for the treatment and diagnosis of diseases including the same; and an expression control method of a target gene using the same.
본 발명은 생활성 핵산을 세포내에 도입할 수 있는 새로운 구조의 핵산 복합체, 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것으로, 더욱 자세하게는, 생활성 핵산과 전체적으로 양전하를 가지도록 변형된 캐리어 펩티드 핵산(Carrier Peptide Nucleic Acid)이 상보적으로 결합된 핵산 복합체 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것이다.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAURLtxIeodPrgW0orgthRFEaSI-_JNR_shSUOSot7eIh7A1QyPeTPNfA2fpAWdB20gmkotLVW99QYvekrq6Oh0AEeMGMZQjWDBNzGS3sSuJd9xsKwxJNFsSI9uHyVJ7749SBT3oNSBIlvMs8mdTcTil7Nsud9dq8MKvm8Q_XjkkJrTpVD5VuVKbYp1uf5v9QEz50QT</recordid><startdate>20180911</startdate><enddate>20180911</enddate><creator>KIM HYE JOO</creator><creator>PARK HEE KYUNG</creator><creator>JEO GOONHO</creator><creator>HUR DEOKHWE</creator><creator>YU JI YEON</creator><creator>BATOCHIR CHINBAYAR</creator><scope>EVB</scope></search><sort><creationdate>20180911</creationdate><title>Peptide Nucleic Acid Complex with Increased Cell Permeability and pharmaceutical composition comprising the same</title><author>KIM HYE JOO ; PARK HEE KYUNG ; JEO GOONHO ; HUR DEOKHWE ; YU JI YEON ; BATOCHIR CHINBAYAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20180100523A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2018</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KIM HYE JOO</creatorcontrib><creatorcontrib>PARK HEE KYUNG</creatorcontrib><creatorcontrib>JEO GOONHO</creatorcontrib><creatorcontrib>HUR DEOKHWE</creatorcontrib><creatorcontrib>YU JI YEON</creatorcontrib><creatorcontrib>BATOCHIR CHINBAYAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KIM HYE JOO</au><au>PARK HEE KYUNG</au><au>JEO GOONHO</au><au>HUR DEOKHWE</au><au>YU JI YEON</au><au>BATOCHIR CHINBAYAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Peptide Nucleic Acid Complex with Increased Cell Permeability and pharmaceutical composition comprising the same</title><date>2018-09-11</date><risdate>2018</risdate><abstract>The present invention relates to a nucleic acid complex with a new structure capable of introducing bioactive nucleic acid into cells, a composition for the treatment and diagnosis of diseases including the same, and an expression control method of a target gene using the same. More specifically, the present invention relates to: a nucleic acid complex where bioactive nucleic acid and carrier peptide nucleic acid modified to generally have a positive charge are complementarily combined to each other; a composition for the treatment and diagnosis of diseases including the same; and an expression control method of a target gene using the same.
본 발명은 생활성 핵산을 세포내에 도입할 수 있는 새로운 구조의 핵산 복합체, 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것으로, 더욱 자세하게는, 생활성 핵산과 전체적으로 양전하를 가지도록 변형된 캐리어 펩티드 핵산(Carrier Peptide Nucleic Acid)이 상보적으로 결합된 핵산 복합체 이를 포함하는 질병의 치료 및 진단용 조성물 및 이를 이용한 표적 유전자의 발현 조절 방법에 관한 것이다.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; kor |
| recordid | cdi_epo_espacenet_KR20180100523A |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Peptide Nucleic Acid Complex with Increased Cell Permeability and pharmaceutical composition comprising the same |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T18%3A30%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KIM%20HYE%20JOO&rft.date=2018-09-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EKR20180100523A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |