IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS
화학식 I의 화합물, 또는 이의 약학적으로 허용 가능한 에스테르, 아미드, 용매화물 또는 염을 제공하고,여기서 R, R, R, R및 R는 본원에 기술된 의미를 갖고, 상기 화합물은 단백질 또는 지질 키나아제 (예를 들어, PI3-K 및/또는 mTOR)의 억제가 바람직하거나 및/또는 필요한 질병 및 특히, 암 또는 증식성 질환의 치료에 유용한 질병 치료에 유용하다. There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given i...
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| creator | OYARZABAL SANTAMARINA JULEN PASTOR FERNANDEZ JOAQUIN MARTINEZ GONZALEZ SONIA |
| description | 화학식 I의 화합물, 또는 이의 약학적으로 허용 가능한 에스테르, 아미드, 용매화물 또는 염을 제공하고,여기서 R, R, R, R및 R는 본원에 기술된 의미를 갖고, 상기 화합물은 단백질 또는 지질 키나아제 (예를 들어, PI3-K 및/또는 mTOR)의 억제가 바람직하거나 및/또는 필요한 질병 및 특히, 암 또는 증식성 질환의 치료에 유용한 질병 치료에 유용하다.
There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20170116250A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20170116250A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20170116250A3</originalsourceid><addsrcrecordid>eNrjZND19PV0cYzyD4gMcozy9HMNVnDzD1IIDXZVcAxW8Pb0cwSyPP08PJ08Q_yDgnkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSbx3kJGBobmBoaGZkamBozFxqgBoeyZy</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS</title><source>esp@cenet</source><creator>OYARZABAL SANTAMARINA JULEN ; PASTOR FERNANDEZ JOAQUIN ; MARTINEZ GONZALEZ SONIA</creator><creatorcontrib>OYARZABAL SANTAMARINA JULEN ; PASTOR FERNANDEZ JOAQUIN ; MARTINEZ GONZALEZ SONIA</creatorcontrib><description>화학식 I의 화합물, 또는 이의 약학적으로 허용 가능한 에스테르, 아미드, 용매화물 또는 염을 제공하고,여기서 R, R, R, R및 R는 본원에 기술된 의미를 갖고, 상기 화합물은 단백질 또는 지질 키나아제 (예를 들어, PI3-K 및/또는 mTOR)의 억제가 바람직하거나 및/또는 필요한 질병 및 특히, 암 또는 증식성 질환의 치료에 유용한 질병 치료에 유용하다.
There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.</description><language>eng ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171018&DB=EPODOC&CC=KR&NR=20170116250A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171018&DB=EPODOC&CC=KR&NR=20170116250A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OYARZABAL SANTAMARINA JULEN</creatorcontrib><creatorcontrib>PASTOR FERNANDEZ JOAQUIN</creatorcontrib><creatorcontrib>MARTINEZ GONZALEZ SONIA</creatorcontrib><title>IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS</title><description>화학식 I의 화합물, 또는 이의 약학적으로 허용 가능한 에스테르, 아미드, 용매화물 또는 염을 제공하고,여기서 R, R, R, R및 R는 본원에 기술된 의미를 갖고, 상기 화합물은 단백질 또는 지질 키나아제 (예를 들어, PI3-K 및/또는 mTOR)의 억제가 바람직하거나 및/또는 필요한 질병 및 특히, 암 또는 증식성 질환의 치료에 유용한 질병 치료에 유용하다.
There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND19PV0cYzyD4gMcozy9HMNVnDzD1IIDXZVcAxW8Pb0cwSyPP08PJ08Q_yDgnkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSbx3kJGBobmBoaGZkamBozFxqgBoeyZy</recordid><startdate>20171018</startdate><enddate>20171018</enddate><creator>OYARZABAL SANTAMARINA JULEN</creator><creator>PASTOR FERNANDEZ JOAQUIN</creator><creator>MARTINEZ GONZALEZ SONIA</creator><scope>EVB</scope></search><sort><creationdate>20171018</creationdate><title>IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS</title><author>OYARZABAL SANTAMARINA JULEN ; PASTOR FERNANDEZ JOAQUIN ; MARTINEZ GONZALEZ SONIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20170116250A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>OYARZABAL SANTAMARINA JULEN</creatorcontrib><creatorcontrib>PASTOR FERNANDEZ JOAQUIN</creatorcontrib><creatorcontrib>MARTINEZ GONZALEZ SONIA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OYARZABAL SANTAMARINA JULEN</au><au>PASTOR FERNANDEZ JOAQUIN</au><au>MARTINEZ GONZALEZ SONIA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS</title><date>2017-10-18</date><risdate>2017</risdate><abstract>화학식 I의 화합물, 또는 이의 약학적으로 허용 가능한 에스테르, 아미드, 용매화물 또는 염을 제공하고,여기서 R, R, R, R및 R는 본원에 기술된 의미를 갖고, 상기 화합물은 단백질 또는 지질 키나아제 (예를 들어, PI3-K 및/또는 mTOR)의 억제가 바람직하거나 및/또는 필요한 질병 및 특히, 암 또는 증식성 질환의 치료에 유용한 질병 치료에 유용하다.
There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS |
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