COMPOSITION FOR PREVENTING, IMPROVING OR TREATING OF TH1-MEDIATED IMMUNE DISEASE OR TH2-MEDIATED IMMUNE DISEASE COMPRISING EXTRACTS FROM CYNANCHYM ATRATUM BUNGE AS AN ACTIVE INGREDIENTS

The present invention relates to a composition comprising a Cynanchum atratum Bunge extract as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. According to the present invention, the Cynanchum atratum Bunge extract has activ...

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Hauptverfasser: CHOI, DAE WOON, JUNG, SUN YOUNG, KANG, CHANG YUIL, DO, JEONG RYONG, CHOI, GYE YOUNG, CHAI, OK HEE, RHO, JEONG HAE, SHIN, HEE SOON, BAE, MIN JUNG, SHON, DONG HWA
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a composition comprising a Cynanchum atratum Bunge extract as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. According to the present invention, the Cynanchum atratum Bunge extract has activities of preventing allergen from passing through intestinal epithelial cells, inhibiting production of IL-4, inhibiting degranulation of mast cells, inducing differentiation into Treg cells, and stabilizing Treg cells, thereby preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases.