TNF-ALPHA ANTIGEN-BINDING PROTEINS WITH INCREASED FCRN BINDING

The present invention provides antigen binding proteins which bind specifically to TNF-alpha. For example novel variants of anti-TNF antibodies such as adalimumab which show increased binding to the FcRn receptor or increased half life compared to adalimumab. Also provided are compositions comprisin...

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Bibliographische Detailangaben

Hauptverfasser:	ELLIS JONATHAN HENRY, SHAH TEJASH, TOMLINSON IAN M, YASIN AHMED, MOLLOY MICHAEL J
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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