2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR
The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions med...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; kor |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KUNG DANIEL WEI SHUNG CAMERON KIMBERLY O'KEEFE FERNANDO DILINIE PRASADHINI SIMILA SUVI TUULA MARJUKKA BHATTACHARYA SAMIT KUMAR MCCLURE KIM FRANCIS LONDREGAN ALLYN TIMOTHY |
| description | The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR20130001276A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR20130001276A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR20130001276A3</originalsourceid><addsrcrecordid>eNqNissKwjAQAHvxIOo_LHg10ge059BszaJsZBMLKlKKxJOooB_hZ0tBPHsamJlx8s4XBRiyeyNOZVYRG2SVqf1G5YtKGdIH7bck7lgsyxM71oxgUKjVgVr0oNlAsEgCO4-gBxH0yjH54MEJELcoQ_m5ZvhhZQU3xCBY4zY4mSajS399xtmXk2TeYKitio97F5-P_hxv8dWtJU-zIk3TLK9KXfx3fQClhT5o</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR</title><source>esp@cenet</source><creator>KUNG DANIEL WEI SHUNG ; CAMERON KIMBERLY O'KEEFE ; FERNANDO DILINIE PRASADHINI ; SIMILA SUVI TUULA MARJUKKA ; BHATTACHARYA SAMIT KUMAR ; MCCLURE KIM FRANCIS ; LONDREGAN ALLYN TIMOTHY</creator><creatorcontrib>KUNG DANIEL WEI SHUNG ; CAMERON KIMBERLY O'KEEFE ; FERNANDO DILINIE PRASADHINI ; SIMILA SUVI TUULA MARJUKKA ; BHATTACHARYA SAMIT KUMAR ; MCCLURE KIM FRANCIS ; LONDREGAN ALLYN TIMOTHY</creatorcontrib><description>The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.</description><language>eng ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130103&DB=EPODOC&CC=KR&NR=20130001276A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130103&DB=EPODOC&CC=KR&NR=20130001276A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUNG DANIEL WEI SHUNG</creatorcontrib><creatorcontrib>CAMERON KIMBERLY O'KEEFE</creatorcontrib><creatorcontrib>FERNANDO DILINIE PRASADHINI</creatorcontrib><creatorcontrib>SIMILA SUVI TUULA MARJUKKA</creatorcontrib><creatorcontrib>BHATTACHARYA SAMIT KUMAR</creatorcontrib><creatorcontrib>MCCLURE KIM FRANCIS</creatorcontrib><creatorcontrib>LONDREGAN ALLYN TIMOTHY</creatorcontrib><title>2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR</title><description>The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNissKwjAQAHvxIOo_LHg10ge059BszaJsZBMLKlKKxJOooB_hZ0tBPHsamJlx8s4XBRiyeyNOZVYRG2SVqf1G5YtKGdIH7bck7lgsyxM71oxgUKjVgVr0oNlAsEgCO4-gBxH0yjH54MEJELcoQ_m5ZvhhZQU3xCBY4zY4mSajS399xtmXk2TeYKitio97F5-P_hxv8dWtJU-zIk3TLK9KXfx3fQClhT5o</recordid><startdate>20130103</startdate><enddate>20130103</enddate><creator>KUNG DANIEL WEI SHUNG</creator><creator>CAMERON KIMBERLY O'KEEFE</creator><creator>FERNANDO DILINIE PRASADHINI</creator><creator>SIMILA SUVI TUULA MARJUKKA</creator><creator>BHATTACHARYA SAMIT KUMAR</creator><creator>MCCLURE KIM FRANCIS</creator><creator>LONDREGAN ALLYN TIMOTHY</creator><scope>EVB</scope></search><sort><creationdate>20130103</creationdate><title>2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR</title><author>KUNG DANIEL WEI SHUNG ; CAMERON KIMBERLY O'KEEFE ; FERNANDO DILINIE PRASADHINI ; SIMILA SUVI TUULA MARJUKKA ; BHATTACHARYA SAMIT KUMAR ; MCCLURE KIM FRANCIS ; LONDREGAN ALLYN TIMOTHY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20130001276A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2013</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KUNG DANIEL WEI SHUNG</creatorcontrib><creatorcontrib>CAMERON KIMBERLY O'KEEFE</creatorcontrib><creatorcontrib>FERNANDO DILINIE PRASADHINI</creatorcontrib><creatorcontrib>SIMILA SUVI TUULA MARJUKKA</creatorcontrib><creatorcontrib>BHATTACHARYA SAMIT KUMAR</creatorcontrib><creatorcontrib>MCCLURE KIM FRANCIS</creatorcontrib><creatorcontrib>LONDREGAN ALLYN TIMOTHY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUNG DANIEL WEI SHUNG</au><au>CAMERON KIMBERLY O'KEEFE</au><au>FERNANDO DILINIE PRASADHINI</au><au>SIMILA SUVI TUULA MARJUKKA</au><au>BHATTACHARYA SAMIT KUMAR</au><au>MCCLURE KIM FRANCIS</au><au>LONDREGAN ALLYN TIMOTHY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR</title><date>2013-01-03</date><risdate>2013</risdate><abstract>The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; kor |
| recordid | cdi_epo_espacenet_KR20130001276A |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 2,3 DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.6]NONANE DERIVATIVES AND THEIR USE AS ANTAGONISTS OR INVERSE AGONISTS OF THE GHRELIN RECEPTOR |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T02%3A19%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KUNG%20DANIEL%20WEI%20SHUNG&rft.date=2013-01-03&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EKR20130001276A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |