HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING

Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an a...

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Hauptverfasser: VENTURINI AMY, TRACEY DANIEL E, KAYMAKCALAN ZEHRA, VELDMAN GEERTRUIDA M, WIDOM ANGELA, DUNCAN ALEXANDER R, WHITE MICHAEL, SMITH STEPHEN, SAKORAFAS PAUL, DU FOU SARAH L, SALFELD JOCHEN G, MYLES ANGELA, FRIEDRICH STUART, ROGUSKA MICHAEL, ELVIN JOHN G, PASKIND MICHAEL, LABKOVSKY BORIS, DERBYSHIRE ELAINE J, BANERJEE SUBHASHIS, WARNE NICHOLAS W, CARMEN SARA, HOLTET THOR LAS
Format: Patent
Sprache:eng ; kor
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