NOVEL COMPOUNDS
The present invention discloses a novel thyroid like compounds of formula (I), wherein R1 R2, R3' R4 and Z are as defined in the specification, method for its preparation, composition containing such compounds and use of such compounds and composition as medicament. Further, compounds of formul...
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| creator | SIDDIQUI M AMIR CHAUTHAIWALE VIJAY MUNSHI SIRALEE DUTT C CHHIPA LAXMIKANT GUPTA RAMESH BHATTAMISRA SUBRAT KUMAR TULI DAVINDER ZAMBAD SHITALKUMAR PUKHARAJ KASUNDRA ASHOK |
| description | The present invention discloses a novel thyroid like compounds of formula (I), wherein R1 R2, R3' R4 and Z are as defined in the specification, method for its preparation, composition containing such compounds and use of such compounds and composition as medicament. Further, compounds of formula (I) has significantly low binding affinity to thyroid receptors and thus considerably devoid of thyrotoxic effects. The invention also relates to the use of the compound of formula (I) for the preparation of a medicament for treating various disease conditions such as obesity, dyslipidemia, metabolic syndrome and co-morbidities associated with metabolic syndrome. |
| format | Patent |
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Further, compounds of formula (I) has significantly low binding affinity to thyroid receptors and thus considerably devoid of thyrotoxic effects. The invention also relates to the use of the compound of formula (I) for the preparation of a medicament for treating various disease conditions such as obesity, dyslipidemia, metabolic syndrome and co-morbidities associated with metabolic syndrome.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100226&DB=EPODOC&CC=KR&NR=20100022104A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100226&DB=EPODOC&CC=KR&NR=20100022104A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SIDDIQUI M AMIR</creatorcontrib><creatorcontrib>CHAUTHAIWALE VIJAY</creatorcontrib><creatorcontrib>MUNSHI SIRALEE</creatorcontrib><creatorcontrib>DUTT C</creatorcontrib><creatorcontrib>CHHIPA LAXMIKANT</creatorcontrib><creatorcontrib>GUPTA RAMESH</creatorcontrib><creatorcontrib>BHATTAMISRA SUBRAT KUMAR</creatorcontrib><creatorcontrib>TULI DAVINDER</creatorcontrib><creatorcontrib>ZAMBAD SHITALKUMAR PUKHARAJ</creatorcontrib><creatorcontrib>KASUNDRA ASHOK</creatorcontrib><title>NOVEL COMPOUNDS</title><description>The present invention discloses a novel thyroid like compounds of formula (I), wherein R1 R2, R3' R4 and Z are as defined in the specification, method for its preparation, composition containing such compounds and use of such compounds and composition as medicament. Further, compounds of formula (I) has significantly low binding affinity to thyroid receptors and thus considerably devoid of thyrotoxic effects. The invention also relates to the use of the compound of formula (I) for the preparation of a medicament for treating various disease conditions such as obesity, dyslipidemia, metabolic syndrome and co-morbidities associated with metabolic syndrome.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOD38w9z9VFw9vcN8A_1cwnmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx3kFGBoYGBgZGRoYGJo7GxKkCAF7AHgY</recordid><startdate>20100226</startdate><enddate>20100226</enddate><creator>SIDDIQUI M AMIR</creator><creator>CHAUTHAIWALE VIJAY</creator><creator>MUNSHI SIRALEE</creator><creator>DUTT C</creator><creator>CHHIPA LAXMIKANT</creator><creator>GUPTA RAMESH</creator><creator>BHATTAMISRA SUBRAT KUMAR</creator><creator>TULI DAVINDER</creator><creator>ZAMBAD SHITALKUMAR PUKHARAJ</creator><creator>KASUNDRA ASHOK</creator><scope>EVB</scope></search><sort><creationdate>20100226</creationdate><title>NOVEL COMPOUNDS</title><author>SIDDIQUI M AMIR ; CHAUTHAIWALE VIJAY ; MUNSHI SIRALEE ; DUTT C ; CHHIPA LAXMIKANT ; GUPTA RAMESH ; BHATTAMISRA SUBRAT KUMAR ; TULI DAVINDER ; ZAMBAD SHITALKUMAR PUKHARAJ ; KASUNDRA ASHOK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20100022104A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SIDDIQUI M AMIR</creatorcontrib><creatorcontrib>CHAUTHAIWALE VIJAY</creatorcontrib><creatorcontrib>MUNSHI SIRALEE</creatorcontrib><creatorcontrib>DUTT C</creatorcontrib><creatorcontrib>CHHIPA LAXMIKANT</creatorcontrib><creatorcontrib>GUPTA RAMESH</creatorcontrib><creatorcontrib>BHATTAMISRA SUBRAT KUMAR</creatorcontrib><creatorcontrib>TULI DAVINDER</creatorcontrib><creatorcontrib>ZAMBAD SHITALKUMAR PUKHARAJ</creatorcontrib><creatorcontrib>KASUNDRA ASHOK</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SIDDIQUI M AMIR</au><au>CHAUTHAIWALE VIJAY</au><au>MUNSHI SIRALEE</au><au>DUTT C</au><au>CHHIPA LAXMIKANT</au><au>GUPTA RAMESH</au><au>BHATTAMISRA SUBRAT KUMAR</au><au>TULI DAVINDER</au><au>ZAMBAD SHITALKUMAR PUKHARAJ</au><au>KASUNDRA ASHOK</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL COMPOUNDS</title><date>2010-02-26</date><risdate>2010</risdate><abstract>The present invention discloses a novel thyroid like compounds of formula (I), wherein R1 R2, R3' R4 and Z are as defined in the specification, method for its preparation, composition containing such compounds and use of such compounds and composition as medicament. Further, compounds of formula (I) has significantly low binding affinity to thyroid receptors and thus considerably devoid of thyrotoxic effects. The invention also relates to the use of the compound of formula (I) for the preparation of a medicament for treating various disease conditions such as obesity, dyslipidemia, metabolic syndrome and co-morbidities associated with metabolic syndrome.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NOVEL COMPOUNDS |
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