ANTIALLERGIC MATERIAL FROM IXERIS DENTATA

A Petasites japonicas extract or Petasites japonicas fermentation of anti-allergic or anti-inflammatory material is provided to have an effect of suppressing degranulation in a RBL-2H3 (Rat mast cell line) without side effect. A Petasites japonicas extract for anti-allergic or anti-inflammatory mate...

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Hauptverfasser: KIM, DONG HYUN, HONG, SUNG SIK, JANG, YOON AH, YOON, HYUNG KWEON, KIM, SANG WOOK, SUH, TAE CHUL
Format: Patent
Sprache:eng
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Zusammenfassung:A Petasites japonicas extract or Petasites japonicas fermentation of anti-allergic or anti-inflammatory material is provided to have an effect of suppressing degranulation in a RBL-2H3 (Rat mast cell line) without side effect. A Petasites japonicas extract for anti-allergic or anti-inflammatory material is obtained by using alcohol, decompressing the extract and culturing with Lactobacillus. The Lactobacillus is Lactobacillus acidophilus (KCTC 3168), Bifidobacterium breve (KCCM 10097) or Bifidobacterium longum (KCCM 100493). A method for producing Petasites japonicas fermentation comprises: a step of dipping a Petasites japonicas in 5% of salt water for one night; a step of adding Lactobacillus and fermenting at 4-15‹C for 1-15 days; and a step of adding 1L of water and extracting, decompressing, and freeze-drying at 90‹C for two hours.