SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

A salicylic acid derivative compound and a pharmaceutical composition containing the same are provided to treat and prevent a brain disorder, ophthalmopathyn pain and inflammation disease, to suppress excitotoxicity and to prevent the damage of stomach caused by the side effect of an anti-inflammato...

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Hauptverfasser: YOON, BOK SEON, AN, CHUN SAN, CHO, JAE YOUNG, LEE, YOUNG AE, LIM, HYANG RAN, GWAG, BYOUNG JOO, BYUN, HAN YEOL, LEE, MOON JUNG, RYU, KEUN SIL, PARK, SUN MI, SHIN, JIN HEE, LEE, JIN HWAN, LEE, JAE KEUN, CHO, SUNG IG, KO, SUN YOUNG
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creator YOON, BOK SEON
AN, CHUN SAN
CHO, JAE YOUNG
LEE, YOUNG AE
LIM, HYANG RAN
GWAG, BYOUNG JOO
BYUN, HAN YEOL
LEE, MOON JUNG
RYU, KEUN SIL
PARK, SUN MI
SHIN, JIN HEE
LEE, JIN HWAN
LEE, JAE KEUN
CHO, SUNG IG
KO, SUN YOUNG
description A salicylic acid derivative compound and a pharmaceutical composition containing the same are provided to treat and prevent a brain disorder, ophthalmopathyn pain and inflammation disease, to suppress excitotoxicity and to prevent the damage of stomach caused by the side effect of an anti-inflammatory agent. A salicylic acid derivative compound or a pharmaceutically allowable salt is indicated as the chemical formula 1. In the chemical formula, X is O or S; R1 is hydrogen or alkyl; R2 is hydrogen, alkyl or alkanoyl; R4 is the phenyl, biphenyl or naphthyl which are substituted or non substituted with at least one selected from the group consisting of halogen, haloalkyl, alkyl, alkoxy, haloalkoxy and nitro; and n is an integer of 2-4.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
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