EPOXIDE INTERMEDIATE IN THE TAMIFLU SYNTHESIS

EPOXIDE INTERMEDIATE IN THE TAMIFLU SYNTHESIS

The present invention relates to technology for preparing derivatives of unsaturated, cyclic, organic acids and salts, thereof. Shikimic acid is an example of such an acid. More particularly, the present invention relates to preparing derivatives of these acids or salts thereof that are esterified,...

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Hauptverfasser: JOHNSTON DAVID A, GABEL RICHARD A, GROANING MICHAEL D
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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creator JOHNSTON DAVID A
GABEL RICHARD A
GROANING MICHAEL D
description The present invention relates to technology for preparing derivatives of unsaturated, cyclic, organic acids and salts, thereof. Shikimic acid is an example of such an acid. More particularly, the present invention relates to preparing derivatives of these acids or salts thereof that are esterified, ketalized, functionalized with a leaving group, and/or provided with epoxide functionality. Preferred aspects may be used in the synthesis of Oseltamivir Phosphate starting from shikimic acid.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title EPOXIDE INTERMEDIATE IN THE TAMIFLU SYNTHESIS
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