STABILIZED ANTI-HEPATITIS B (HBV) ANTIBODY FORMULATIONS

STABILIZED ANTI-HEPATITIS B (HBV) ANTIBODY FORMULATIONS

The present invention provides liquid formulations of antibodies or fragments thereof that specifically bind to a hepatitis B virus (HBV) antigen, which formulations exhibit stability, low to undetectable levels of aggregations, and very little to no loss of the biological activities of the antibodi...

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Hauptverfasser: EREN RACHEL, O'CONNOR SANDRA, MISRA HEMANT KUMAR, GOWAN WALTER G. JR, DAGAN SHLOMO
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator EREN RACHEL
O'CONNOR SANDRA
MISRA HEMANT KUMAR
GOWAN WALTER G. JR
DAGAN SHLOMO
description The present invention provides liquid formulations of antibodies or fragments thereof that specifically bind to a hepatitis B virus (HBV) antigen, which formulations exhibit stability, low to undetectable levels of aggregations, and very little to no loss of the biological activities of the antibodies or antibody fragments, even during long periods of storage. Furthermore, the invention provides methods of preventing, treating or ameliorating one or more symptoms associated with HBV infection utilizing the liquid formulations of the present invention.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title STABILIZED ANTI-HEPATITIS B (HBV) ANTIBODY FORMULATIONS
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