PROCESS FOR PREPARING CRYSTALLINE FORM I OF OLANZAPINE

A process for preparing olanzapine Form I comprises: a) cooling a concentrated solution of olanzapine; b) isolating wet crystals of olanzapine Form I; and c) drying wet crystals and recovering olanzapine Form 1. Drying can be conducted by stepwise increases in the drying temperatures, with extended...

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Hauptverfasser: DAYARAM VISHAL PARMAR, PANDURANG SHARAT NARSAPUR, SUNDARAM VENKATARAMAN, SITARAM HITENDRA CHAUDHARY, BOMMAREDDY SIVA KUMAR REDDY
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creator DAYARAM VISHAL PARMAR
PANDURANG SHARAT NARSAPUR
SUNDARAM VENKATARAMAN
SITARAM HITENDRA CHAUDHARY
BOMMAREDDY SIVA KUMAR REDDY
description A process for preparing olanzapine Form I comprises: a) cooling a concentrated solution of olanzapine; b) isolating wet crystals of olanzapine Form I; and c) drying wet crystals and recovering olanzapine Form 1. Drying can be conducted by stepwise increases in the drying temperatures, with extended holding times at each temperature condition.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR PREPARING CRYSTALLINE FORM I OF OLANZAPINE
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