MUTANT OF GRANULOCYTE-COLONY STIMULATING FACTOR(G-CSF) AND CHEMICALLY CONJUGATED POLYPEPTIDE THEREOF

A mutant of granulocyte-colony stimulating factor(G-CSF) and a chemically conjugated polypeptide thereof are provided to increase the retention time of G-CSF in human body without reduction of biological activity by introducing cysteine into the G-CSF, so that in vivo activity of G-CSF is maintained...

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Bibliographische Detailangaben
Hauptverfasser: HONG, JEUNG WOON, KANG, KWAN YUB
Format: Patent
Sprache:eng
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