GUANIDINO-SUBSTITUTED QUINAZOLINONE COMPOUNDS AS MC4-R AGONISTS
A variety of small molecule, guanidine- containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined her...
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| creator | MUSSO DAVID L CONLEE CHRISTOPHER R CHU DANIEL THOMPSON BRIAN D DE ARMAS KUNTZ JUDITH CHAUDER BRIAN A SMITH AARON BISHOP MICHAEL J SWAIN WILLIAM R AURRECOECHEA NATALIA SPEAKE JASON D THOMSON STEPHEN A DU KIEN S BOYCE RUSTUM S BARVIAN KEVIN K |
| description | A variety of small molecule, guanidine- containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined herein. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | GUANIDINO-SUBSTITUTED QUINAZOLINONE COMPOUNDS AS MC4-R AGONISTS |
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