COMPOSITION COMPRISING EXTRACT OF ASTILBE RUBRA OR ASTILBIC ACID AND PELTOBOYKINOLIC ACID DERIVATIVES WHICH HAS ANTI-INFLAMMATORY OR ANTI-ALLERGIC ACTIVITIES BY INHIBITING LYSOPAF-ACETYLTRANSFERASE AND 5-LIPOXYGENASE

PURPOSE: Provided is a composition having anti-inflammatory or anti-allergic activity which comprises the extract of Astilbe rubra or astilbic acid and peltoboykinolic acid derivatives. Therefore, the composition inhibits the activity of lysoPAF-acetyltransferase which synthesizes PAF, and 5-lipoxyg...

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Bibliographische Detailangaben
Hauptverfasser:	BAE, GI HWAN, PARK, JAE DON, KIM, HYEON PYO, JANG, HYEON UK, SON, GEON HO, KANG, SAM SIK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PURPOSE: Provided is a composition having anti-inflammatory or anti-allergic activity which comprises the extract of Astilbe rubra or astilbic acid and peltoboykinolic acid derivatives. Therefore, the composition inhibits the activity of lysoPAF-acetyltransferase which synthesizes PAF, and 5-lipoxygenase which synthesizes eicosanoid. CONSTITUTION: The pharmaceutical composition for preventing and treating inflammatory and atopic diseases is characterized by containing 0.01-50% of: the crude extract of Astilbe rubra using methanol or the nonpolar solvent soluble extrct of Astilbe rubra using hexan, as active ingredients; or astilbic acid and peltoboykinolic acid derivatives or their pharmaceutically acceptable salts.