TUBERCULOSIS-SPECIFIC ANTIGEN AND DIAGNOSTIC KIT USING THE SAME TO ACCOMPLISH RAPID AND ACCURATE DIAGNOSIS OF TUBERCULOSIS

PURPOSE: A tuberculosis-specific antigen and a diagnostic kit using the same are provided. The antigen has improved sensitivity and specificity to an antibody. Therefore, rapid and accurate diagnosis of tuberculosis can be accomplished. CONSTITUTION: A method for diagnosis of tuberculosis comprises...

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Hauptverfasser: BANG, YEONG JU, CHO, BEOM SU, LEE, SEONG EUN, KIM, JONG WAN, LIM, YUN, SIM, YEONG SU, KIM, DAE GI, CHO, IL SANG, HAN, SEONG GU, JANG, JIN UK, JUNG, DU IL, LEE, DAE YEON, LEE, HO SUN, HWANG, GYU CHUN, PARK, SE YEONG
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:PURPOSE: A tuberculosis-specific antigen and a diagnostic kit using the same are provided. The antigen has improved sensitivity and specificity to an antibody. Therefore, rapid and accurate diagnosis of tuberculosis can be accomplished. CONSTITUTION: A method for diagnosis of tuberculosis comprises the steps of: (1) obtaining a biological sample containing at least Mt-1 antibody of Mycobacterium tuberculosis; (2) obtaining purified recombinant protein containing the Mt-1 antigen; (3) adding the biological sample into the recombinant protein to form an antigen-antibody complex; and (4) detecting the antigen-antibody complex, wherein the biological sample is selected from blood, serum, urine and saliva; the recombinant protein further contains any one or more selected from 38kD, 16kD, Mt-12 and Mt-13; and the detection is carried out by using enzyme-linked immunoassay, radiation immunoassay, fluorescence immunoassay, particle agglutination, precipitation and in situ coloring analysis.