An organic acid salt of amlodipine

PURPOSE: Novel organic acid salt of amlodipine is provided which is excellent in physico-chemical properties. And its manufacture method and a pharmaceutical composition containing it are provided. CONSTITUTION: Amlodipine ethanesulfonic acid salt is represented by the formula(2) and has crystallize...

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Hauptverfasser: CHO, SEONG HWAN, PARK, CHUNG SIL, JUNG, EUN JU, PARK, GYEONG MI, YOON, YONG SIK, LIM, DONG GWON, JIN, HAE TAK, KIM, YEONG HUN, KANG, HYEON SEOK, JUNG, YUN TAEK, JUNG, SEONG HAK, LEE, HYEOK GU, LEE, GWANG HYEOK, KIM, YUN CHEOL, LEE, SEONG HAK, YOEN, GYU JEONG, CHUN, JUN HUI
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Sprache:eng ; kor
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creator CHO, SEONG HWAN
PARK, CHUNG SIL
JUNG, EUN JU
PARK, GYEONG MI
YOON, YONG SIK
LIM, DONG GWON
JIN, HAE TAK
KIM, YEONG HUN
KANG, HYEON SEOK
JUNG, YUN TAEK
JUNG, SEONG HAK
LEE, HYEOK GU
LEE, GWANG HYEOK
KIM, YUN CHEOL
LEE, SEONG HAK
YOEN, GYU JEONG
CHUN, JUN HUI
description PURPOSE: Novel organic acid salt of amlodipine is provided which is excellent in physico-chemical properties. And its manufacture method and a pharmaceutical composition containing it are provided. CONSTITUTION: Amlodipine ethanesulfonic acid salt is represented by the formula(2) and has crystallized form. It is manufactured by reaction of amlodipine and ethanesulfonic acid in an inert solvent. A pharmaceutical composition contains a therapeutically effective amount of amlodipine ethanesulfonic acid salt and a pharmaceutically acceptable diluent or carrier. 본 발명은 물리화학적 성질이 우수한 암로디핀의 신규 유기산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물에 관한 것이다.
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And its manufacture method and a pharmaceutical composition containing it are provided. CONSTITUTION: Amlodipine ethanesulfonic acid salt is represented by the formula(2) and has crystallized form. It is manufactured by reaction of amlodipine and ethanesulfonic acid in an inert solvent. A pharmaceutical composition contains a therapeutically effective amount of amlodipine ethanesulfonic acid salt and a pharmaceutically acceptable diluent or carrier. 본 발명은 물리화학적 성질이 우수한 암로디핀의 신규 유기산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물에 관한 것이다.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title An organic acid salt of amlodipine
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