3-SUBSTITUTED-D-HOMO-1,3,5,(10)-ESTRATRIENE DERIVATIVES

PURPOSE: Estratriene derivatives of the following formula have a powerful inhibitory effect on estrone sulfatase and are hence useful for the prophylaxis or treatment of diseases caused by estrogens, such as breast cancer, uterine cancer, ovarian cancer, endometriosis, adenomyosis uteri and mayoralt...

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Hauptverfasser:	KOIZUMI NAOYUKI, KAWACHI TOMOKO, TAKEGAWA SHIGEHIRO, IWASHITA SHIGEKI, FUJII TOMOHITO, MIEDA MAMORU
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES STEROIDS
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creator	KOIZUMI NAOYUKI KAWACHI TOMOKO TAKEGAWA SHIGEHIRO IWASHITA SHIGEKI FUJII TOMOHITO MIEDA MAMORU
description	PURPOSE: Estratriene derivatives of the following formula have a powerful inhibitory effect on estrone sulfatase and are hence useful for the prophylaxis or treatment of diseases caused by estrogens, such as breast cancer, uterine cancer, ovarian cancer, endometriosis, adenomyosis uteri and mayoralty. CONSTITUTION: In the formula, one of A and B represents C=O or CH2 and the other represents O or NH; and R represents -SO2NR(1)R(2) or -PO(OM)2 in which R(1) and R(2) each independently represent a hydrogen atom or a lower alkyl group and M represents a hydrogen atom or an alkali metal; provided that, when one of A and B represents NH, the other represents C=O.
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CONSTITUTION: In the formula, one of A and B represents C=O or CH2 and the other represents O or NH; and R represents -SO2NR(1)R(2) or -PO(OM)2 in which R(1) and R(2) each independently represent a hydrogen atom or a lower alkyl group and M represents a hydrogen atom or an alkali metal; provided that, when one of A and B represents NH, the other represents C=O.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; STEROIDS</subject><creationdate>2000</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20000626&DB=EPODOC&CC=KR&NR=20000035979A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20000626&DB=EPODOC&CC=KR&NR=20000035979A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KOIZUMI NAOYUKI</creatorcontrib><creatorcontrib>KAWACHI TOMOKO</creatorcontrib><creatorcontrib>TAKEGAWA SHIGEHIRO</creatorcontrib><creatorcontrib>IWASHITA SHIGEKI</creatorcontrib><creatorcontrib>FUJII TOMOHITO</creatorcontrib><creatorcontrib>MIEDA MAMORU</creatorcontrib><title>3-SUBSTITUTED-D-HOMO-1,3,5,(10)-ESTRATRIENE DERIVATIVES</title><description>PURPOSE: Estratriene derivatives of the following formula have a powerful inhibitory effect on estrone sulfatase and are hence useful for the prophylaxis or treatment of diseases caused by estrogens, such as breast cancer, uterine cancer, ovarian cancer, endometriosis, adenomyosis uteri and mayoralty. CONSTITUTION: In the formula, one of A and B represents C=O or CH2 and the other represents O or NH; and R represents -SO2NR(1)R(2) or -PO(OM)2 in which R(1) and R(2) each independently represent a hydrogen atom or a lower alkyl group and M represents a hydrogen atom or an alkali metal; provided that, when one of A and B represents NH, the other represents C=O.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2000</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDA31g0OdQoO8QwJDXF10XXR9fD39dc11DHWMdXRMDTQ1HUNDglyDAnydPVzVXBxDfIMcwzxDHMN5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8d5BRgYgYGxqaW7paEycKgCEQChm</recordid><startdate>20000626</startdate><enddate>20000626</enddate><creator>KOIZUMI NAOYUKI</creator><creator>KAWACHI TOMOKO</creator><creator>TAKEGAWA SHIGEHIRO</creator><creator>IWASHITA SHIGEKI</creator><creator>FUJII TOMOHITO</creator><creator>MIEDA MAMORU</creator><scope>EVB</scope></search><sort><creationdate>20000626</creationdate><title>3-SUBSTITUTED-D-HOMO-1,3,5,(10)-ESTRATRIENE DERIVATIVES</title><author>KOIZUMI NAOYUKI ; KAWACHI TOMOKO ; TAKEGAWA SHIGEHIRO ; IWASHITA SHIGEKI ; FUJII TOMOHITO ; MIEDA MAMORU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20000035979A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2000</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>KOIZUMI NAOYUKI</creatorcontrib><creatorcontrib>KAWACHI TOMOKO</creatorcontrib><creatorcontrib>TAKEGAWA SHIGEHIRO</creatorcontrib><creatorcontrib>IWASHITA SHIGEKI</creatorcontrib><creatorcontrib>FUJII TOMOHITO</creatorcontrib><creatorcontrib>MIEDA MAMORU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KOIZUMI NAOYUKI</au><au>KAWACHI TOMOKO</au><au>TAKEGAWA SHIGEHIRO</au><au>IWASHITA SHIGEKI</au><au>FUJII TOMOHITO</au><au>MIEDA MAMORU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-SUBSTITUTED-D-HOMO-1,3,5,(10)-ESTRATRIENE DERIVATIVES</title><date>2000-06-26</date><risdate>2000</risdate><abstract>PURPOSE: Estratriene derivatives of the following formula have a powerful inhibitory effect on estrone sulfatase and are hence useful for the prophylaxis or treatment of diseases caused by estrogens, such as breast cancer, uterine cancer, ovarian cancer, endometriosis, adenomyosis uteri and mayoralty. CONSTITUTION: In the formula, one of A and B represents C=O or CH2 and the other represents O or NH; and R represents -SO2NR(1)R(2) or -PO(OM)2 in which R(1) and R(2) each independently represent a hydrogen atom or a lower alkyl group and M represents a hydrogen atom or an alkali metal; provided that, when one of A and B represents NH, the other represents C=O.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES STEROIDS
title	3-SUBSTITUTED-D-HOMO-1,3,5,(10)-ESTRATRIENE DERIVATIVES
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