Depression prevention and treatment composition for postmenopausal women comprising the extract of Salvia miltiorrhiza as an active ingredient

The present invention relates to a composition for preventing and treating depression of menopausal women including an extract of Salvia miltiorrhiza BUNGE as an active ingredient. According to the present invention, the extract of Salvia miltiorrhiza BUNGE controls secretion of luteinizing hormones...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KWON JEONG EUN, SUH HEEJU, KANG SE CHAN, HER YANGMI
Format: Patent
Sprache:eng ; kor
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Beschreibung
Zusammenfassung:The present invention relates to a composition for preventing and treating depression of menopausal women including an extract of Salvia miltiorrhiza BUNGE as an active ingredient. According to the present invention, the extract of Salvia miltiorrhiza BUNGE controls secretion of luteinizing hormones and follicle stimulating hormones and increases secretion of serotonin and norepinephrine, thereby preventing, alleviating and treating a change in hormones and depression occurring after menopause. In addition, the composition containing an extract of Salvia miltiorrhiza BUNGE including danshensu as an active ingredient continuously maintains its effect during long-term storage by having excellent stability of raw materials, and thus has high industrial applicability. Therefore, the composition including an extract of Salvia miltiorrhiza BUNGE as an active ingredient controls hormones of menopausal women, and can be used as a pharmaceutical composition for preventing and treating depression of menopausal women, or as a health-aid food composition for preventing and alleviating depression of menopausal women. 본 발명은 단삼 추출물을 포함하는 폐경기 여성의 우울증 예방 및 치료용 조성물에 관한 것으로, 본 발명의 단삼 추출물은 황체형성호르몬과 여포자극호르몬의 분비를 조절하며, 세로토닌과 노르에피네프린의 분비를 증가시켜 폐경기 후 발생하는 호르몬 변화와 우울증을 예방, 개선 및 치료하는 것을 특징으로 한다. 또한, 원료의 안정성 또한 뛰어나므로 단신수를 포함하는 단삼 추출물을 유효성분으로 포함하는 조성물의 경우 장기간 보관시 효능이 지속적으로 유지되므로 산업화 소재로 이용하기에 적합하다. 따라서, 본 발명의 단삼 추출물을 유효성분으로 포함하는 조성물은 폐경기 여성의 호르몬을 조절하여 폐경기 여성의 우울증 예방 및 치료용 약학적 조성물 또는 폐경기 여성의 우울증 예방 및 개선용 건강기능식품 조성물로 적용될 수 있다.