HEPATITIS B VACCINE

본원은 변이 HBsAg 단백질 또는 B형 간염 바이러스 표면 항원의 항원성을 나타내는 그의단편을 기술한다. 이러한 변이 단백질 또는 이의 단편은 HBsAg 서열(vHBsAg)의 위치 145에서 글리신 이외의 다른 아미노산이 존재하는 변형된 a 결정소를 함유한다. 또한, 본원은 vHBsAg를 함유한 백신, 항-vHBsAg 항체의 시험관내 진단검색용키트, 및 항-vHBsAg 항체를 함유한 항체제제를 제공한다. A variant HBsAg protein of fragment thereof displaying the antigenicity...

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Hauptverfasser:	THOMAS, HOWARD CHRISTOPHER, CARMAN, WILLIAM FREDERICK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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creator	THOMAS, HOWARD CHRISTOPHER CARMAN, WILLIAM FREDERICK
description	본원은 변이 HBsAg 단백질 또는 B형 간염 바이러스 표면 항원의 항원성을 나타내는 그의단편을 기술한다. 이러한 변이 단백질 또는 이의 단편은 HBsAg 서열(vHBsAg)의 위치 145에서 글리신 이외의 다른 아미노산이 존재하는 변형된 a 결정소를 함유한다. 또한, 본원은 vHBsAg를 함유한 백신, 항-vHBsAg 항체의 시험관내 진단검색용키트, 및 항-vHBsAg 항체를 함유한 항체제제를 제공한다. A variant HBsAg protein of fragment thereof displaying the antigenicity of Hepatitis B virus surface antigen is disclosed, in which the variant protein or fragment thereof (vHBsAg) comprises a modified a determinant in which there is an amino acid other than glycine at position 145 of the HBsAg sequence. A vaccine comprising the vHBsAg is provided, as it is a kit for diagnostic in vitro detection of anti-vHBsAg antibodies and an antibody preparation comprising anti-vHBsAg antibodies.
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fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_KR100208129BB1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>KR100208129BB1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_KR100208129BB13</originalsourceid><addsrcrecordid>eNrjZBD2cA1wDPEM8QxWcFIIc3R29vRz5WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8d5BhgYGRgYWhkaWTk6GxsSpAgDBRh8S</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HEPATITIS B VACCINE</title><source>esp@cenet</source><creator>THOMAS, HOWARD CHRISTOPHER ; CARMAN, WILLIAM FREDERICK</creator><creatorcontrib>THOMAS, HOWARD CHRISTOPHER ; CARMAN, WILLIAM FREDERICK</creatorcontrib><description>본원은 변이 HBsAg 단백질 또는 B형 간염 바이러스 표면 항원의 항원성을 나타내는 그의단편을 기술한다. 이러한 변이 단백질 또는 이의 단편은 HBsAg 서열(vHBsAg)의 위치 145에서 글리신 이외의 다른 아미노산이 존재하는 변형된 a 결정소를 함유한다. 또한, 본원은 vHBsAg를 함유한 백신, 항-vHBsAg 항체의 시험관내 진단검색용키트, 및 항-vHBsAg 항체를 함유한 항체제제를 제공한다. A variant HBsAg protein of fragment thereof displaying the antigenicity of Hepatitis B virus surface antigen is disclosed, in which the variant protein or fragment thereof (vHBsAg) comprises a modified a determinant in which there is an amino acid other than glycine at position 145 of the HBsAg sequence. A vaccine comprising the vHBsAg is provided, as it is a kit for diagnostic in vitro detection of anti-vHBsAg antibodies and an antibody preparation comprising anti-vHBsAg antibodies.</description><edition>6</edition><language>eng ; kor</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990715&DB=EPODOC&CC=KR&NR=100208129B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990715&DB=EPODOC&CC=KR&NR=100208129B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>THOMAS, HOWARD CHRISTOPHER</creatorcontrib><creatorcontrib>CARMAN, WILLIAM FREDERICK</creatorcontrib><title>HEPATITIS B VACCINE</title><description>본원은 변이 HBsAg 단백질 또는 B형 간염 바이러스 표면 항원의 항원성을 나타내는 그의단편을 기술한다. 이러한 변이 단백질 또는 이의 단편은 HBsAg 서열(vHBsAg)의 위치 145에서 글리신 이외의 다른 아미노산이 존재하는 변형된 a 결정소를 함유한다. 또한, 본원은 vHBsAg를 함유한 백신, 항-vHBsAg 항체의 시험관내 진단검색용키트, 및 항-vHBsAg 항체를 함유한 항체제제를 제공한다. A variant HBsAg protein of fragment thereof displaying the antigenicity of Hepatitis B virus surface antigen is disclosed, in which the variant protein or fragment thereof (vHBsAg) comprises a modified a determinant in which there is an amino acid other than glycine at position 145 of the HBsAg sequence. A vaccine comprising the vHBsAg is provided, as it is a kit for diagnostic in vitro detection of anti-vHBsAg antibodies and an antibody preparation comprising anti-vHBsAg antibodies.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBD2cA1wDPEM8QxWcFIIc3R29vRz5WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8d5BhgYGRgYWhkaWTk6GxsSpAgDBRh8S</recordid><startdate>19990715</startdate><enddate>19990715</enddate><creator>THOMAS, HOWARD CHRISTOPHER</creator><creator>CARMAN, WILLIAM FREDERICK</creator><scope>EVB</scope></search><sort><creationdate>19990715</creationdate><title>HEPATITIS B VACCINE</title><author>THOMAS, HOWARD CHRISTOPHER ; CARMAN, WILLIAM FREDERICK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR100208129BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>1999</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>THOMAS, HOWARD CHRISTOPHER</creatorcontrib><creatorcontrib>CARMAN, WILLIAM FREDERICK</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THOMAS, HOWARD CHRISTOPHER</au><au>CARMAN, WILLIAM FREDERICK</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HEPATITIS B VACCINE</title><date>1999-07-15</date><risdate>1999</risdate><abstract>본원은 변이 HBsAg 단백질 또는 B형 간염 바이러스 표면 항원의 항원성을 나타내는 그의단편을 기술한다. 이러한 변이 단백질 또는 이의 단편은 HBsAg 서열(vHBsAg)의 위치 145에서 글리신 이외의 다른 아미노산이 존재하는 변형된 a 결정소를 함유한다. 또한, 본원은 vHBsAg를 함유한 백신, 항-vHBsAg 항체의 시험관내 진단검색용키트, 및 항-vHBsAg 항체를 함유한 항체제제를 제공한다. A variant HBsAg protein of fragment thereof displaying the antigenicity of Hepatitis B virus surface antigen is disclosed, in which the variant protein or fragment thereof (vHBsAg) comprises a modified a determinant in which there is an amino acid other than glycine at position 145 of the HBsAg sequence. A vaccine comprising the vHBsAg is provided, as it is a kit for diagnostic in vitro detection of anti-vHBsAg antibodies and an antibody preparation comprising anti-vHBsAg antibodies.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
title	HEPATITIS B VACCINE
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