ALPHA-GLYCOSYL CERAMIDE DERIVATIVE

NEW MATERIAL:A compound shown by formula I [one of R1 and R2 is H and the other is OH; one of R3 and R4 is H and the other is OH or hexapyranosyl of (1 4) bond; X1 and X2 are H or bonded to form double bond; n is 10-25]. EXAMPLE:2-Azido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-galactopyranosyl 1-1(3-O-ben...

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Hauptverfasser: KATO TAKAO, NAKANO KOICHI, HASHIMOTO HIRONOBU, KANAKI REIJI
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creator KATO TAKAO
NAKANO KOICHI
HASHIMOTO HIRONOBU
KANAKI REIJI
description NEW MATERIAL:A compound shown by formula I [one of R1 and R2 is H and the other is OH; one of R3 and R4 is H and the other is OH or hexapyranosyl of (1 4) bond; X1 and X2 are H or bonded to form double bond; n is 10-25]. EXAMPLE:2-Azido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-galactopyranosyl 1-1(3-O-benzoyl) ceramide. USE:An antigen for sensitization. PREPARATION:Triphenylphosphine is added to azide part of an alpha-(2-azido-2- deoxyhexopyranosyl) ceramide derivative shown by formula II (one of R1 and R2 is H and the other is lower acyloxy; R6 is lower acyl; R7 is OH-protecting group), the resultant compound is hydrolyzed to convert the azide group to an amino group, the amino group is acetylated, the protecting group R7 is eliminated and the lower acyloxy group is converted into OH.
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subjects CHEMISTRY
CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS
DERIVATIVES THEREOF
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
SUGARS
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
TESTING
title ALPHA-GLYCOSYL CERAMIDE DERIVATIVE
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