PRODUCTION OF 3-(1-SUBSTITUTED-PYRIDINIO)THIOMETHYL-DELTA3-CEPHEM-4-CARBOXYLATE DERIVATIVE
NEW MATERIAL:A compound of formula I (R , R are lower alkyl). EXAMPLE:Diphenylmethyl (Z)-7-[alpha-(2-amino-4-thiazolyl)-alpha-(methoxyimino) acetamide]-3-(1-acetonyl-4-pyridinio)thiomethyl-DELTA -cephem-4-carb oxylate chloride. USE:Antibacterial against gram-positive and gram-negative bacteria inclu...
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| creator | TAKAHASHI TAKUMI YAMAZAKI ATSUKI SHIBANUMA TADAO |
| description | NEW MATERIAL:A compound of formula I (R , R are lower alkyl). EXAMPLE:Diphenylmethyl (Z)-7-[alpha-(2-amino-4-thiazolyl)-alpha-(methoxyimino) acetamide]-3-(1-acetonyl-4-pyridinio)thiomethyl-DELTA -cephem-4-carb oxylate chloride. USE:Antibacterial against gram-positive and gram-negative bacteria including Pseudomonas areuginosa. Additive for feed and preservative. PREPARATION:The reaction of 3-substituted methyl-DELTA -cephem-4-carboxylate derivative or salt of compound III (R is halogen; R is H, protection group for carboxyl; R is H, amino-protecting group) with 1-substituted-2- or -4- thiopyridone or 1-substituted-3-mercaptopyridinium of formulas IV-VI is followed, when desired, by deprotection to give the compound of formula I. |
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EXAMPLE:Diphenylmethyl (Z)-7-[alpha-(2-amino-4-thiazolyl)-alpha-(methoxyimino) acetamide]-3-(1-acetonyl-4-pyridinio)thiomethyl-DELTA -cephem-4-carb oxylate chloride. USE:Antibacterial against gram-positive and gram-negative bacteria including Pseudomonas areuginosa. Additive for feed and preservative. PREPARATION:The reaction of 3-substituted methyl-DELTA -cephem-4-carboxylate derivative or salt of compound III (R is halogen; R is H, protection group for carboxyl; R is H, amino-protecting group) with 1-substituted-2- or -4- thiopyridone or 1-substituted-3-mercaptopyridinium of formulas IV-VI is followed, when desired, by deprotection to give the compound of formula I.</description><language>eng</language><subject>CHEMISTRY ; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS ; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC ; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS ; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</subject><creationdate>1988</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19880216&DB=EPODOC&CC=JP&NR=S6335581A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19880216&DB=EPODOC&CC=JP&NR=S6335581A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAKAHASHI TAKUMI</creatorcontrib><creatorcontrib>YAMAZAKI ATSUKI</creatorcontrib><creatorcontrib>SHIBANUMA TADAO</creatorcontrib><title>PRODUCTION OF 3-(1-SUBSTITUTED-PYRIDINIO)THIOMETHYL-DELTA3-CEPHEM-4-CARBOXYLATE DERIVATIVE</title><description>NEW MATERIAL:A compound of formula I (R , R are lower alkyl). EXAMPLE:Diphenylmethyl (Z)-7-[alpha-(2-amino-4-thiazolyl)-alpha-(methoxyimino) acetamide]-3-(1-acetonyl-4-pyridinio)thiomethyl-DELTA -cephem-4-carb oxylate chloride. USE:Antibacterial against gram-positive and gram-negative bacteria including Pseudomonas areuginosa. Additive for feed and preservative. PREPARATION:The reaction of 3-substituted methyl-DELTA -cephem-4-carboxylate derivative or salt of compound III (R is halogen; R is H, protection group for carboxyl; R is H, amino-protecting group) with 1-substituted-2- or -4- thiopyridone or 1-substituted-3-mercaptopyridinium of formulas IV-VI is followed, when desired, by deprotection to give the compound of formula I.</description><subject>CHEMISTRY</subject><subject>CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS</subject><subject>GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC</subject><subject>GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS</subject><subject>TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1988</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEOgjAQAFAWB6P-Q0cdbiAV41raIz0DtGkPIi6EmDoZJcH_j4sf4PSWt85uPjjTaSbXClcJCfscYldGJu4YDfghkKGW3IEtuQbZDjUYrFlJ0OgtNnAErULprkOtGIXBQL1i6nGbrR7Tc0m7n5tMVMjaQprfY1rm6Z5e6TNefDxJWRTnXMk_yhcUhDHz</recordid><startdate>19880216</startdate><enddate>19880216</enddate><creator>TAKAHASHI TAKUMI</creator><creator>YAMAZAKI ATSUKI</creator><creator>SHIBANUMA TADAO</creator><scope>EVB</scope></search><sort><creationdate>19880216</creationdate><title>PRODUCTION OF 3-(1-SUBSTITUTED-PYRIDINIO)THIOMETHYL-DELTA3-CEPHEM-4-CARBOXYLATE DERIVATIVE</title><author>TAKAHASHI TAKUMI ; YAMAZAKI ATSUKI ; SHIBANUMA TADAO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPS6335581A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1988</creationdate><topic>CHEMISTRY</topic><topic>CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS</topic><topic>GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC</topic><topic>GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS</topic><topic>TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</topic><toplevel>online_resources</toplevel><creatorcontrib>TAKAHASHI TAKUMI</creatorcontrib><creatorcontrib>YAMAZAKI ATSUKI</creatorcontrib><creatorcontrib>SHIBANUMA TADAO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TAKAHASHI TAKUMI</au><au>YAMAZAKI ATSUKI</au><au>SHIBANUMA TADAO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PRODUCTION OF 3-(1-SUBSTITUTED-PYRIDINIO)THIOMETHYL-DELTA3-CEPHEM-4-CARBOXYLATE DERIVATIVE</title><date>1988-02-16</date><risdate>1988</risdate><abstract>NEW MATERIAL:A compound of formula I (R , R are lower alkyl). EXAMPLE:Diphenylmethyl (Z)-7-[alpha-(2-amino-4-thiazolyl)-alpha-(methoxyimino) acetamide]-3-(1-acetonyl-4-pyridinio)thiomethyl-DELTA -cephem-4-carb oxylate chloride. USE:Antibacterial against gram-positive and gram-negative bacteria including Pseudomonas areuginosa. Additive for feed and preservative. PREPARATION:The reaction of 3-substituted methyl-DELTA -cephem-4-carboxylate derivative or salt of compound III (R is halogen; R is H, protection group for carboxyl; R is H, amino-protecting group) with 1-substituted-2- or -4- thiopyridone or 1-substituted-3-mercaptopyridinium of formulas IV-VI is followed, when desired, by deprotection to give the compound of formula I.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE |
| title | PRODUCTION OF 3-(1-SUBSTITUTED-PYRIDINIO)THIOMETHYL-DELTA3-CEPHEM-4-CARBOXYLATE DERIVATIVE |
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