ANTHRACYCLINE DERIVATIVES AND BIOLOGICAL MANUFACTURE

1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represen...

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Hauptverfasser: BIMARU NARETSUSHIYU GANGURI, KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN, HANSU PEETERU KUREEMERU, TORIPUTEIKUMAA MUKOOPADEIIAI, KURISUTOFUAA MIRUTON MASHIYUU FURANKO, HANSU BUORUFURAMU FUEERUHAABERU
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creator BIMARU NARETSUSHIYU GANGURI
KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN
HANSU PEETERU KUREEMERU
TORIPUTEIKUMAA MUKOOPADEIIAI
KURISUTOFUAA MIRUTON MASHIYUU FURANKO
HANSU BUORUFURAMU FUEERUHAABERU
description 1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof. 1. Claims for the contracting State AT A process for the preparation of compounds of the Formula I see diagramm : EP0186807,P11,F1 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof, which comprises fermentation of the microorganism Streptomyces purpurascens DSM 2658 in a customary manner under aerobic conditions, in the presence of a nutrient medium, addition of a chemical inhibitor after a particular fermentation time, and isolation, from the culture liquid and the mycelium, of the compounds which have been formed, using organic solvents followed by chromatography in a customary manner.
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Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof. 1. Claims for the contracting State AT A process for the preparation of compounds of the Formula I see diagramm : EP0186807,P11,F1 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof, which comprises fermentation of the microorganism Streptomyces purpurascens DSM 2658 in a customary manner under aerobic conditions, in the presence of a nutrient medium, addition of a chemical inhibitor after a particular fermentation time, and isolation, from the culture liquid and the mycelium, of the compounds which have been formed, using organic solvents followed by chromatography in a customary manner.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; DERIVATIVES THEREOF ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>1986</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19860702&amp;DB=EPODOC&amp;CC=JP&amp;NR=S61145145A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19860702&amp;DB=EPODOC&amp;CC=JP&amp;NR=S61145145A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BIMARU NARETSUSHIYU GANGURI</creatorcontrib><creatorcontrib>KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN</creatorcontrib><creatorcontrib>HANSU PEETERU KUREEMERU</creatorcontrib><creatorcontrib>TORIPUTEIKUMAA MUKOOPADEIIAI</creatorcontrib><creatorcontrib>KURISUTOFUAA MIRUTON MASHIYUU FURANKO</creatorcontrib><creatorcontrib>HANSU BUORUFURAMU FUEERUHAABERU</creatorcontrib><title>ANTHRACYCLINE DERIVATIVES AND BIOLOGICAL MANUFACTURE</title><description>1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof. 1. Claims for the contracting State AT A process for the preparation of compounds of the Formula I see diagramm : EP0186807,P11,F1 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof, which comprises fermentation of the microorganism Streptomyces purpurascens DSM 2658 in a customary manner under aerobic conditions, in the presence of a nutrient medium, addition of a chemical inhibitor after a particular fermentation time, and isolation, from the culture liquid and the mycelium, of the compounds which have been formed, using organic solvents followed by chromatography in a customary manner.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1986</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBx9AvxCHJ0jnT28fRzVXBxDfIMcwzxDHMNVnD0c1Fw8vT38Xf3dHb0UfB19At1c3QOCQ1y5WFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8V4BwWaGhiamQORoTIwaAOPIJ9c</recordid><startdate>19860702</startdate><enddate>19860702</enddate><creator>BIMARU NARETSUSHIYU GANGURI</creator><creator>KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN</creator><creator>HANSU PEETERU KUREEMERU</creator><creator>TORIPUTEIKUMAA MUKOOPADEIIAI</creator><creator>KURISUTOFUAA MIRUTON MASHIYUU FURANKO</creator><creator>HANSU BUORUFURAMU FUEERUHAABERU</creator><scope>EVB</scope></search><sort><creationdate>19860702</creationdate><title>ANTHRACYCLINE DERIVATIVES AND BIOLOGICAL MANUFACTURE</title><author>BIMARU NARETSUSHIYU GANGURI ; KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN ; HANSU PEETERU KUREEMERU ; TORIPUTEIKUMAA MUKOOPADEIIAI ; KURISUTOFUAA MIRUTON MASHIYUU FURANKO ; HANSU BUORUFURAMU FUEERUHAABERU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPS61145145A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1986</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>BIMARU NARETSUSHIYU GANGURI</creatorcontrib><creatorcontrib>KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN</creatorcontrib><creatorcontrib>HANSU PEETERU KUREEMERU</creatorcontrib><creatorcontrib>TORIPUTEIKUMAA MUKOOPADEIIAI</creatorcontrib><creatorcontrib>KURISUTOFUAA MIRUTON MASHIYUU FURANKO</creatorcontrib><creatorcontrib>HANSU BUORUFURAMU FUEERUHAABERU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BIMARU NARETSUSHIYU GANGURI</au><au>KARIANAPURAMU RAAJIYAGOPARAN DESHIKAN</au><au>HANSU PEETERU KUREEMERU</au><au>TORIPUTEIKUMAA MUKOOPADEIIAI</au><au>KURISUTOFUAA MIRUTON MASHIYUU FURANKO</au><au>HANSU BUORUFURAMU FUEERUHAABERU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTHRACYCLINE DERIVATIVES AND BIOLOGICAL MANUFACTURE</title><date>1986-07-02</date><risdate>1986</risdate><abstract>1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof. 1. Claims for the contracting State AT A process for the preparation of compounds of the Formula I see diagramm : EP0186807,P11,F1 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof, which comprises fermentation of the microorganism Streptomyces purpurascens DSM 2658 in a customary manner under aerobic conditions, in the presence of a nutrient medium, addition of a chemical inhibitor after a particular fermentation time, and isolation, from the culture liquid and the mycelium, of the compounds which have been formed, using organic solvents followed by chromatography in a customary manner.</abstract><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title ANTHRACYCLINE DERIVATIVES AND BIOLOGICAL MANUFACTURE
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