NOVEL SUBSTITUTED ISOCHROMAN AND OXEPIN COMPOUND

Isochromans and oxepines of the formula (I) in which R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms or, together with R , denotes an alkylene group having 3 to 5 C atoms, R...

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Hauptverfasser: IRUSE SUTORERAA, HERUBERUTO KOTSUPE, FURANTSU ESEE, RIKARUTO RAIHERU, BUORUFUGANGU ABERE, BUORUFUGANGU HOEFUKE, BUORUFURAMU GAIDA, BERUNAA TORAUNETSUKAA
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creator IRUSE SUTORERAA
HERUBERUTO KOTSUPE
FURANTSU ESEE
RIKARUTO RAIHERU
BUORUFUGANGU ABERE
BUORUFUGANGU HOEFUKE
BUORUFURAMU GAIDA
BERUNAA TORAUNETSUKAA
description Isochromans and oxepines of the formula (I) in which R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms or, together with R , denotes an alkylene group having 3 to 5 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having 1 to 6 C atoms or a pyridinyl group, R denotes a hydrogen atom, a fluorine, chlorine or bromine atom, a straight or branched alkyl group having 1 to 6 C atoms, a hydroxyl or alkoxy group having 1 to 4 C atoms or a trifluoromethyl group, R denotes a hydrogen atom, a fluorine, chlorine or bromine atom, a straight or branched alkyl group having 1 to 6 C atoms, a hydroxyl or alkoxy group having 1 to 4 C atoms or, together with R , denotes a methylenedioxy group, R denotes a hydrogen atom, or a hydroxyl or alkoxy group having 1 to 4 C atoms, m denotes the numbers 1 or 2 and n denotes the numbers 1, 2 or 3, and their acid addition salts. The compounds have calcium antagonist and antihypertensive activity.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL SUBSTITUTED ISOCHROMAN AND OXEPIN COMPOUND
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