NOVEL SUBSTITUTED ISOCHROMAN AND OXEPIN COMPOUND

NOVEL SUBSTITUTED ISOCHROMAN AND OXEPIN COMPOUND

Isochromans and oxepines of the formula (I) in which R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms or, together with R , denotes an alkylene group having 3 to 5 C atoms, R...

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Bibliographische Detailangaben
Hauptverfasser: IRUSE SUTORERAA, HERUBERUTO KOTSUPE, FURANTSU ESEE, RIKARUTO RAIHERU, BUORUFUGANGU ABERE, BUORUFUGANGU HOEFUKE, BUORUFURAMU GAIDA, BERUNAA TORAUNETSUKAA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Isochromans and oxepines of the formula (I) in which R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms or, together with R , denotes an alkylene group having 3 to 5 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having up to 4 C atoms, R denotes a hydrogen atom or a straight or branched alkyl group having 1 to 6 C atoms or a pyridinyl group, R denotes a hydrogen atom, a fluorine, chlorine or bromine atom, a straight or branched alkyl group having 1 to 6 C atoms, a hydroxyl or alkoxy group having 1 to 4 C atoms or a trifluoromethyl group, R denotes a hydrogen atom, a fluorine, chlorine or bromine atom, a straight or branched alkyl group having 1 to 6 C atoms, a hydroxyl or alkoxy group having 1 to 4 C atoms or, together with R , denotes a methylenedioxy group, R denotes a hydrogen atom, or a hydroxyl or alkoxy group having 1 to 4 C atoms, m denotes the numbers 1 or 2 and n denotes the numbers 1, 2 or 3, and their acid addition salts. The compounds have calcium antagonist and antihypertensive activity.