DETERMINATION METHOD OF POLYAMINE

PURPOSE:To enable the determination of polyamine also usable for clinical test, by using polyamine oxidase M. CONSTITUTION:A fungus such as Penicillium sp. No. PO-1 (FERM-P 5685) belonging to the genus Penicillium, capable of producing polyamine oxidase M, is aerobically cultivated to give polyamine...

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Bibliographische Detailangaben
Hauptverfasser: AZUMA TOSHIHIKO, MACHIDA HARUO, HORIKOSHI KOUKI, IWASAKI SHINJIROU, KOBAYASHI YOSHINORI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To enable the determination of polyamine also usable for clinical test, by using polyamine oxidase M. CONSTITUTION:A fungus such as Penicillium sp. No. PO-1 (FERM-P 5685) belonging to the genus Penicillium, capable of producing polyamine oxidase M, is aerobically cultivated to give polyamine oxidase, which is treated with a specimen containing a polyamine such as spermidine, spermine, acetylspermidine, acetylspermine, etc. The amount of oxygen consumed in the treatment or the amount of hydrogen peroxide formed is determined by a conventional procedure.