ANTIINFLUENZAL AGENT AND NEW OLIGORIBONUCLEOTIDE

PROBLEM TO BE SOLVED: To provide an antiinfluenzal agent capable of extremely effectively suppressing the expression of protein. SOLUTION: This antiinfluenzal agent contains, as an active component, a capped oligoribonucleotide expressed by formula m GpppXpY (ppp is triphosphate bridge; p is monopho...

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Hauptverfasser:	TAKAI KAZUYUKI, ISHIKAWA MASAHIDE, HATTA TOSHIFUMI, TAKAKU HIROSHI, MIURA KINICHIRO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide an antiinfluenzal agent capable of extremely effectively suppressing the expression of protein. SOLUTION: This antiinfluenzal agent contains, as an active component, a capped oligoribonucleotide expressed by formula m GpppXpY (ppp is triphosphate bridge; p is monophosphate bridge; m G is 7-methylguanosine group; X is 2'-O-methylguanosine group or guanosine group; Y is an oligoribonucleotide having 5-11 bases) and capable of bonding with PB2 protein of influenza virus RNA polymerase.