NOVEL ANTITUMOR COMPOUND
PROBLEM TO BE SOLVED: To obtain a novel peptide and its salts that have excellent antitumor action. SOLUTION: This peptide is represented by the formula. The compound of the formula is obtained by culturing Streptomyces nobilis (for example, JCM 4274 strain or the like) in a culture medium containin...
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| creator | HIRAMOTO MASASHI TAKEBAYASHI YUKIHIRO NAGAI KOJI HAYATA KINYA |
| description | PROBLEM TO BE SOLVED: To obtain a novel peptide and its salts that have excellent antitumor action. SOLUTION: This peptide is represented by the formula. The compound of the formula is obtained by culturing Streptomyces nobilis (for example, JCM 4274 strain or the like) in a culture medium containing L-arabinose, meat essence and the like at a pH of 6-8, at a temperature of 25-30 deg.C under aerobic conditions. The daily dose of the peptide of the formula is preferably in the range of 50-200 mg/adult. |
| format | Patent |
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The compound of the formula is obtained by culturing Streptomyces nobilis (for example, JCM 4274 strain or the like) in a culture medium containing L-arabinose, meat essence and the like at a pH of 6-8, at a temperature of 25-30 deg.C under aerobic conditions. The daily dose of the peptide of the formula is preferably in the range of 50-200 mg/adult.</description><edition>6</edition><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990706&DB=EPODOC&CC=JP&NR=H11180997A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990706&DB=EPODOC&CC=JP&NR=H11180997A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HIRAMOTO MASASHI</creatorcontrib><creatorcontrib>TAKEBAYASHI YUKIHIRO</creatorcontrib><creatorcontrib>NAGAI KOJI</creatorcontrib><creatorcontrib>HAYATA KINYA</creatorcontrib><title>NOVEL ANTITUMOR COMPOUND</title><description>PROBLEM TO BE SOLVED: To obtain a novel peptide and its salts that have excellent antitumor action. SOLUTION: This peptide is represented by the formula. The compound of the formula is obtained by culturing Streptomyces nobilis (for example, JCM 4274 strain or the like) in a culture medium containing L-arabinose, meat essence and the like at a pH of 6-8, at a temperature of 25-30 deg.C under aerobic conditions. 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SOLUTION: This peptide is represented by the formula. The compound of the formula is obtained by culturing Streptomyces nobilis (for example, JCM 4274 strain or the like) in a culture medium containing L-arabinose, meat essence and the like at a pH of 6-8, at a temperature of 25-30 deg.C under aerobic conditions. The daily dose of the peptide of the formula is preferably in the range of 50-200 mg/adult.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | NOVEL ANTITUMOR COMPOUND |
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